Structure of cytotrophoblast

Known as: Cellular trophoblast, Cytotrophoblasts, Cytotrophoblastic cell 
Trophoblasts with single nucleus and defined cellular structures. As the PLACENTA develops, pockets of cytotrophoblasts serve as stem cells for… (More)
National Institutes of Health

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Structure of extraembryonic mesoblastStructure of placental membrane

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trophoblast

Papers overview

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Highly Cited
2000
Highly Cited
2000
Human cytomegalovirus infection of placental cytotrophoblasts in vitro and in utero: implications for transmission and pathogenesis.
Human cytomegalovirus (CMV) is the leading cause of prenatal viral infection. Affected infants may suffer intrauterine growth… (More)
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Highly Cited
1998
Highly Cited
1998
Villous cytotrophoblast regulation of the syncytial apoptotic cascade in the human placenta
 Villous trophoblast in the human placenta consists of a population of proliferating stem cells which differentiate and… (More)
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Highly Cited
1997
Highly Cited
1997
Human cytotrophoblasts adopt a vascular phenotype as they differentiate. A strategy for successful endovascular invasion?
Establishment of the human placenta requires that fetal cytotrophoblast stem cells in anchoring chorionic villi become invasive… (More)
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Highly Cited
1997
Highly Cited
1997
Preeclampsia is associated with failure of human cytotrophoblasts to mimic a vascular adhesion phenotype. One cause of defective endovascular invasion in this syndrome?
In human pregnancy, placental cytotrophoblasts that invade the uterus downregulate the expression of adhesion receptors that are… (More)
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Highly Cited
1997
Highly Cited
1997
Activin is a local regulator of human cytotrophoblast cell differentiation.
Cytotrophoblast cells of the first trimester placenta are highly invasive when removed from villi and cultured in vitro. In vivo… (More)
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Highly Cited
1995
Highly Cited
1995
Human placental HLA-G expression is restricted to differentiated cytotrophoblasts.
Human placental trophoblasts lie at the maternal-fetal interface, a position in which they could play an important role in… (More)
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Highly Cited
1993
Highly Cited
1993
Preeclampsia is associated with abnormal expression of adhesion molecules by invasive cytotrophoblasts.
In normal human pregnancy, invasion of the uterus and its arterial system by cytotrophoblasts extends through the entire decidua… (More)
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Highly Cited
1992
Highly Cited
1992
Distribution patterns of extracellular matrix components and adhesion receptors are intricately modulated during first trimester cytotrophoblast differentiation along the invasive pathway, in vivo.
Development of the human embryo depends on the ability of first trimester cytotrophoblastic stem cells to differentiate and… (More)
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Highly Cited
1991
Highly Cited
1991
92-kD type IV collagenase mediates invasion of human cytotrophoblasts
The specialized interaction between embryonic and maternal tissues is unique to mammalian development. This interaction begins… (More)
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Highly Cited
1986
Highly Cited
1986
Purification, characterization, and in vitro differentiation of cytotrophoblasts from human term placentae.
Highly purified functional cytotrophoblasts have been prepared from human term placentae by adding a Percoll gradient… (More)
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