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Structural Genomics

The combination of computational DNA sequence analysis with structural determinations by X-ray crystallography and NMR techniques to study protein… 
National Institutes of Health

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2013
2013
Improving the soluble expression of recombinant proteins by randomly shuffling 5' and 3' coding-sequence ends.
Many structural genomics (SG) programmes rely on the design of soluble protein domains. The production and screening of large… 
Review
2012
Review
2012
Structural Analysis of Hypothetical Proteins from Helicobacter pylori: An Approach to Estimate Functions of Unknown or Hypothetical Proteins
Helicobacter pylori (H. pylori) have a unique ability to survive in extreme acidic environments and to colonize the gastric… 
2012
2012
Assessing the accuracy of template-based structure prediction metaservers by comparison with structural genomics structures
The explosion of the size of the universe of known protein sequences has stimulated two complementary approaches to structural… 
Review
2010
Review
2010
Personal remarks on the future of protein crystallography and structural biology.
Protein crystallography, the main experimental method of structural biology, has undergone in the recent past three revolutionary… 
2010
2010
Functional Analysis of Sequence Variation In silico structure-function analysis of pathological variation in the HSD 11 B 2 gene sequence
Manning JR, Bailey MA, Soares DC, Dunbar DR, Mullins JJ. In silico structure-function analysis of pathological variation in the… 
2008
2008
Structural Genomics and Structural Proteomics: A Global Perspective
The concept of Structural Genomics (SG) arose towards the mid-1990sas a consequence of the availability of whole-genome… 
2004
2004
The structural genomics experimental pipeline: Insights from global target lists
Structural genomics (SG) initiatives are currently attempting to achieve the high‐throughput determination of protein structures… 
Review
2004
Review
2004
Crystallization data mining in structural genomics: using positive and negative results to optimize protein crystallization screens.
2003
2003
ÄZQ heißt jetzt Ärztliches Zentrum für Qualität in der Medizin
Onkologie/Kolonkarzinom,Hämatologie sowie die ethischen,sozialen und Kostenaspekte der Genomik in Diagnostik und Therapie… 
2003
2003
Cardio(blood-lymph)vascular genomics: need for a terminology adjustment.
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