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Structural Genomics

The combination of computational DNA sequence analysis with structural determinations by X-ray crystallography and NMR techniques to study protein… 
National Institutes of Health

Papers overview

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2013
2013
Improving the soluble expression of recombinant proteins by randomly shuffling 5' and 3' coding-sequence ends.
Many structural genomics (SG) programmes rely on the design of soluble protein domains. The production and screening of large… 
2012
2012
Assessing the accuracy of template-based structure prediction metaservers by comparison with structural genomics structures
The explosion of the size of the universe of known protein sequences has stimulated two complementary approaches to structural… 
2010
2010
Functional Analysis of Sequence Variation In silico structure-function analysis of pathological variation in the HSD 11 B 2 gene sequence
Manning JR, Bailey MA, Soares DC, Dunbar DR, Mullins JJ. In silico structure-function analysis of pathological variation in the… 
2008
2008
Structural Genomics and Structural Proteomics: A Global Perspective
The concept of Structural Genomics (SG) arose towards the mid-1990sas a consequence of the availability of whole-genome… 
Review
2004
Review
2004
Crystallization data mining in structural genomics: using positive and negative results to optimize protein crystallization screens.
2003
2003
Cardio(blood-lymph)vascular genomics: need for a terminology adjustment.
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