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Streptogramin Group B

Known as: Group B Streptogramin, Streptogramin, Group B, Group B Streptogramins 
A structural subclass of streptogramins. They are cyclic hexadepsipeptides with approximate molecular weight of 800 that contain a characteristic 3… 
National Institutes of Health

Related topics

Related topics

9 relations

Broader (1)

Anti-Bacterial Agents
In Bloodagonistsanalogs & derivativesantagonists & inhibitors

Narrower (1)

virginiamycin factor S1

Papers overview

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Highly Cited
2017
Highly Cited
2017
Metagenomic analysis reveals wastewater treatment plants as hotspots of antibiotic resistance genes and mobile genetic elements.
Review
2005
Review
2005
Improving on nature: antibiotics that target the ribosome.
  • J. Sutcliffe
  • Current opinion in microbiology
  • 2005
  • Corpus ID: 1491061
Review
2003
Review
2003
Occurrence and spread of antibiotic resistances in Enterococcus faecium.
Highly Cited
2001
Highly Cited
2001
Vgb from Staphylococcus aureus inactivates streptogramin B antibiotics by an elimination mechanism not hydrolysis.
The streptogramin antibiotics were identified almost 50 years ago but have only recently found clinical use as a consequence of… 
Review
1995
Review
1995
Erythromycin resistance by ribosome modification
  • B. Weisblum
  • Antimicrobial agents and chemotherapy
  • 1995
  • Corpus ID: 2951780
Erythromycin inhibits protein synthesis by its effect on ribosome function (14, 118, 119). The metabolic modifications that… 
Highly Cited
1995
Highly Cited
1995
Critical influence of resistance to streptogramin B-type antibiotics on activity of RP 59500 (quinupristin-dalfopristin) in experimental endocarditis due to Staphylococcus aureus
In order to determine the microbiological and pharmacokinetic parameters that best predicted the in vivo antistaphylococcal… 
Highly Cited
1992
Highly Cited
1992
Activity of RP 59500, a new parenteral semisynthetic streptogramin, against staphylococci with various mechanisms of resistance to macrolide-lincosamide-streptogramin antibiotics.
RP 59500 is a semisynthetic streptogramin (Sg) composed of two synergic components: RP 57669 and RP 54476. The activities of RP… 
Highly Cited
1989
Highly Cited
1989
New macrolides active against Streptococcus pyogenes with inducible or constitutive type of macrolide-lincosamide-streptogramin B resistance
Macrolide-resistant bacteria can be classified as inducibly resistant or constitutively resistant. Inducibly resistant bacteria… 
Highly Cited
1985
Highly Cited
1985
Nucleotide sequence of ermA, a macrolide-lincosamide-streptogramin B determinant in Staphylococcus aureus
  • E. Murphy
  • Journal of bacteriology
  • 1985
  • Corpus ID: 12774505
The complete nucleotide sequence of ermA, the prototype macrolide-lincosamide-streptogramin B resistance gene from Staphylococcus… 
Highly Cited
1977
Highly Cited
1977
Cooperative and antagonistic interactions of peptidyl-tRNA and antibiotics with bacterial ribosomes.
There is a single-site interaction of [methylene-14C]thiamphenicol and [methylene-14C]chloramphenicol with run-off ribosomes with… 
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