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Stat3 Signaling Pathway

STATs, Signal Transducers and Activators of Transcription, are transcription factors that are phosphorylated by JAK kinases in response to cytokine… 
National Institutes of Health

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10 relations
FRAP1 protein, humanJAK1 protein, humanJAK1 wt AlleleJAK3 wt Allele

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2014
2014
BRMS1 Regulates Apoptosis in Non-small Cell Lung Cancer Cells
Breast cancer metastasis suppressor 1 (BRMS1) was originally identified as a metastasis suppressor gene in human breast cancer… 
2012
2012
Abstract 3876: Role of Stat3 transcriptional activation in a preclinical mouse model of prostate cancer and potential as a therapeutic target
The transcription factor, Stat3, has been implicated in the growth and progression of several cancer types including lung skin… 
2012
2012
Abstract 5178: Evaluation of lumican expression profiles in prostate cancer
Proceedings: AACR 103rd Annual Meeting 2012‐‐ Mar 31‐Apr 4, 2012; Chicago, IL The transcription factor, Stat3, has been… 
2011
2011
[Effects of blocking activation of IGF-1-Stat3 signaling pathway in guinea pig sclera fibroblast by AG490 on expression of MMP-2 and Integrinβ(1)].
OBJECTIVE To explore the effect of Blocking activation of IGF-1-Stat3 signaling pathway in guinea pig sclera fibroblast (GSFs) by… 
2007
2007
Role of Stat3 signaling pathway in induction of MMPs expression by angiotensin II in human colon cancer cell lines
Objective To investigate the role of Stat3 in the induction of MMPs expression by angiotensin Ⅱ(AngⅡ)in human colon cancer cell… 
2006
2006
Stat3 Signaling Pathway Regulates the Expression of Caspase-3 and Promotes Apoptosis of Human Colon Cancer Cells
Objective The purpose of the study was to examine colon cancer cell lines to determine whether Stat3/Caspase-3 plays an important… 
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