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Spondyloepimetaphyseal Dysplasia, Aggrecan Type
Known as:
SEMD, Aggrecan Type
National Institutes of Health
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Related topics
Related topics
3 relations
ACAN, ASP2267ASN
Broader (2)
Bone Diseases, Developmental
Craniofacial Abnormalities
Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
2020
2020
The role of cartilage glycosaminoglycan structure in gagCEST
E. Einarsson
,
P. Peterson
,
+6 authors
J. Svensson
NMR in Biomedicine
2020
Corpus ID: 210950628
Glycosaminoglycan (GAG) chemical exchange saturation transfer (gagCEST) is a potential method for cartilage quality assessment…
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Highly Cited
2015
Highly Cited
2015
Interleukin‐1 Acts via the JNK‐2 Signaling Pathway to Induce Aggrecan Degradation by Human Chondrocytes
H. Ismail
,
Kazuhiro Yamamoto
,
T. Vincent
,
H. Nagase
,
L. Troeberg
,
J. Saklatvala
Arthritis & Rheumatology
2015
Corpus ID: 7208826
Aggrecan enables articular cartilage to bear load and resist compression. Aggrecan loss occurs early in osteoarthritis and…
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2010
2010
Quantification of aggrecan fragments in synovial fluid and urine using a high-throughput LC / MS / MS assay
A. Malfait
,
M. Tortorella
,
C. Anglin
,
D. Dufield
,
S. Settle
,
O. Nemirovskiy
2010
Corpus ID: 34027978
INTRODUCTION: Aggrecanase (ADAMTS-4/-5)-mediated degradation of the aggrecan core protein is a key pathological event in…
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2010
2010
IONIC EFFECTS AND SELF-ASSEMBLY IN THE SOLUTION OF THE BIOPOLYMER AGGRECAN
F. Horkay
2010
Corpus ID: 17057505
It is noteworthy that degradative changes in the size and structure of aggrecan become more progressive with age. This process…
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2006
2006
Cartilage elasticity resides in shape module decoran and aggrecan sumps of damping fluid: implications in osteoarthrosis
John E. Scott
,
R. Stockwell
Journal of Physiology
2006
Corpus ID: 22449883
Cartilage ultrastructure is based on collagen fibrils tied together by proteoglycans (PGs). Interfibrillar orthogonal PG bridges…
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2005
2005
Products resulting from cleavage of the interglobular domain of aggrecan in samples of synovial fluid collected from dogs with early- and late-stage osteoarthritis.
J. Innes
,
C. Little
,
C. Hughes
,
B. Caterson
American Journal of Veterinary Research
2005
Corpus ID: 31373188
OBJECTIVE To investigate interglobular domain (IGD) cleavage of aggrecan in dogs with naturally developing osteoarthritis (OA…
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Highly Cited
2005
Highly Cited
2005
Lack of tissue inhibitor of metalloproteinases-3 results in an enhanced inflammatory response in antigen-induced arthritis.
M. Mahmoodi
,
S. Sahebjam
,
D. Smookler
,
R. Khokha
,
John S. Mort
American Journal of Pathology
2005
Corpus ID: 262652967
2002
2002
Tensile Loading Promotes Fibrochondrocyte Differentiation of Mesenchymal Progenitors and Initial Development of Engineered Fibrocartilage Constructs
J. Connelly
,
C. Wilson
,
M. Levenston
2002
Corpus ID: 41187199
Introduction: Bone marrow stromal cells (BMSCs) are an attractive cell source for fibrocartilage repair due to their multipotency…
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1996
1996
Changes in cartilage proteoglycan aggrecan after intra-articular injection of interleukin-1 in rabbits: studies of synovial fluid and articular cartilage.
C. Lundberg
,
I. Asberg
,
M. Ionescu
,
A. Reiner
,
G. Smedegård
,
A. Poole
Annals of the Rheumatic Diseases
1996
Corpus ID: 37838574
OBJECTIVE: To determine how acute but transient inflammation affects the cartilage proteoglycan aggrecan and the value of…
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Highly Cited
1993
Highly Cited
1993
Fibroblast and neutrophil collagenases cleave at two sites in the cartilage aggrecan interglobular domain.
A. Fosang
,
K. Last
,
+5 authors
J. Hamilton
Biochemical Journal
1993
Corpus ID: 24327191
The actions of recombinant human fibroblast collagenase (MMP1), purified polymorphonuclear leucocyte collagenase (MMP8) and their…
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