Spondyloepimetaphyseal Dysplasia, Aggrecan Type
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Glycosaminoglycan (GAG) chemical exchange saturation transfer (gagCEST) is a potential method for cartilage quality assessment… Expand Aggrecanases from the ADAMTS (A Disintegrin And Metalloproteinase with ThromboSpondin motifs) family are important therapeutic… Expand Bone marrow derived mesenchymal stem cells (MSCs) can be used to repair articular cartilage defects, these cells should be… Expand It is noteworthy that degradative changes in the size and structure of aggrecan become more progressive with age. This process… Expand INTRODUCTION: Aggrecanase (ADAMTS-4/-5)-mediated degradation of the aggrecan core protein is a key pathological event in… Expand The large aggregating proteoglycan, aggrecan, better known for its physiological role in articular cartilage where it serves to… Expand OBJECTIVE
To investigate interglobular domain (IGD) cleavage of aggrecan in dogs with naturally developing osteoarthritis (OA… Expand Introduction: Bone marrow stromal cells (BMSCs) are an attractive cell source for fibrocartilage repair due to their multipotency… Expand Dear Editor: There is accumulating in vitro and in vivo evidence demonstrating that a subset of chondrocytes can survive and… Expand OBJECTIVE: To determine how acute but transient inflammation affects the cartilage proteoglycan aggrecan and the value of… Expand