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Spheroids, Cellular

Known as: Cellular Spheroids, Spheroid, Multicellular, Multicellular Spheroids 
Spherical, heterogeneous aggregates of proliferating, quiescent, and necrotic cells in culture that retain three-dimensional architecture and tissue… 
National Institutes of Health

Related topics

Related topics

10 relations
Cell hybridizationClone CellsCultured Cell LineHybrid Cells

Broader (1)

Cultured Cells

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Review
2003
Review
2003
A strategy for the development of tissue engineering scaffolds that regulate cell behavior.
Review
1998
Review
1998
Reversal of intrinsic and acquired forms of drug resistance by hyaluronidase treatment of solid tumors.
Highly Cited
1995
Highly Cited
1995
A microplate assay for quantitation of anchorage-independent growth of transformed cells.
We developed a 96-well microplate assay to quantitate anchorage-independent growth of transformed cells. Wells of tissue culture… 
Highly Cited
1994
Highly Cited
1994
Correlation between immune and vascular activities of xanthenone acetic acid antitumor agents.
To determine whether xanthenone acetic acid (XAA) analogues of flavone acetic acid (FAA) have similar ischemic and nonischemic… 
Highly Cited
1994
Highly Cited
1994
Rapid acquisition of multicellular drug resistance after a single exposure of mammary tumor cells to antitumor alkylating agents.
BACKGROUND Clinical drug resistance is either intrinsic (de novo) or often acquired rapidly in conjunction with chemotherapy. By… 
Highly Cited
1990
Highly Cited
1990
Formation of multicellular spheroids composed of adult rat hepatocytes in dishes with positively charged surfaces and under other nonadherent environments.
Highly Cited
1989
Highly Cited
1989
Blood flow failure as a major determinant in the antitumor action of flavone acetic acid.
Some investigators have suggested that the marked activity of flavone acetic acid (FAA) against advanced solid tumors in mice… 
Highly Cited
1986
Highly Cited
1986
Proliferative and clonogenic heterogeneity of cells from EMT6/Ro multicellular spheroids induced by the glucose and oxygen supply.
The culture of EMT6/Ro multicellular tumor spheroids in a 20-fold range of glucose concentrations and a 4-fold range of oxygen… 
Highly Cited
1985
Highly Cited
1985
The radiobiology of human neuroblastoma.
Highly Cited
1984
Highly Cited
1984
Effect of cell-cell interactions on drug sensitivity and growth of drug-sensitive and -resistant tumor cells in spheroids.
Multicellular spheroids were grown from mixtures of rat brain tumor cells sensitive (9L) and resistant (R3) to 1,3-bis(2… 
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