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Spheroids, Cellular

Known as: Cellular Spheroids, Spheroid, Multicellular, Multicellular Spheroids 
Spherical, heterogeneous aggregates of proliferating, quiescent, and necrotic cells in culture that retain three-dimensional architecture and tissue… 
National Institutes of Health

Related topics

Related topics

10 relations
Cell hybridizationClone CellsCultured Cell LineHybrid Cells

Broader (1)

Cultured Cells

Papers overview

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2001
2001
Expression in UVW glioma cells of the noradrenaline transporter gene, driven by the telomerase RNA promoter, induces active uptake of [131I]MIBG and clonogenic cell kill
One of the most effective ways to kill cancer cells is by treatment of tumours with radiation. However, the administered dose of… 
Highly Cited
2000
Highly Cited
2000
Redox regulation of P‐glycoprotein‐mediated multidrug resistance in multicellular prostate tumor spheroids
Multicellular prostate tumor spheroids develop intrinsic P‐glycoprotein (Pgp)–mediated multidrug resistance with the appearance… 
1999
1999
Collateral expression of proangiogenic and tumorigenic properties in intestinal epithelial cell variants selected for resistance to anoikis.
Although in vitro anchorage-independent growth is widely used as a marker of cell transformation, the biological implications of… 
Review
1996
Review
1996
Induction and reversal of cell adhesion-dependent multicellular drug resistance in solid breast tumors.
Although there are a number of chemotherapeutic drugs available for the treatment of breast cancer, eg. adriamycin… 
Highly Cited
1994
Highly Cited
1994
Rapid acquisition of multicellular drug resistance after a single exposure of mammary tumor cells to antitumor alkylating agents.
BACKGROUND Clinical drug resistance is either intrinsic (de novo) or often acquired rapidly in conjunction with chemotherapy. By… 
Highly Cited
1994
Highly Cited
1994
Correlation between immune and vascular activities of xanthenone acetic acid antitumor agents.
To determine whether xanthenone acetic acid (XAA) analogues of flavone acetic acid (FAA) have similar ischemic and nonischemic… 
Highly Cited
1994
Highly Cited
1994
Selective down-regulation of integrin receptors in spheroids of squamous cell carcinoma.
Integrin expression in squamous cell carcinomas have been reported to be down-regulated in vivo. Because integrins are molecules… 
Highly Cited
1990
Highly Cited
1990
Smooth muscle-derived factor stimulates mobility of human tumor cells.
Invasion of normal tissues is a complex process which requires active locomotion of malignant cells. Recent studies have… 
1987
1987
The radiation response of a human colon adenocarcinoma grown in monolayer, as spheroids, and in nude mice.
A human colon adenocarcinoma cell line, WiDr, has been grown in monolayer, as multicellular spheroids, and as xenografted tumors… 
1975
1975
A comparative study of post-irradiation growth kinetics of spheroids and monolayers.
Post-irradiation growth kinetics of gamma-irradiated spheroid and monolayer cells in exponential growth phase was investigated by… 
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