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Spheroids, Cellular
Known as:
Cellular Spheroids
, Spheroid, Multicellular
, Multicellular Spheroids
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Spherical, heterogeneous aggregates of proliferating, quiescent, and necrotic cells in culture that retain three-dimensional architecture and tissue…
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National Institutes of Health
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Related topics
Related topics
10 relations
Cell hybridization
Clone Cells
Cultured Cell Line
Hybrid Cells
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Broader (1)
Cultured Cells
Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
Review
2003
Review
2003
A strategy for the development of tissue engineering scaffolds that regulate cell behavior.
T. Takezawa
Biomaterials
2003
Corpus ID: 20804170
Review
1998
Review
1998
Reversal of intrinsic and acquired forms of drug resistance by hyaluronidase treatment of solid tumors.
B. S. Croix
,
S. Man
,
R. Kerbel
,
R. Kerbel
Cancer Letters
1998
Corpus ID: 35920911
Highly Cited
1995
Highly Cited
1995
A microplate assay for quantitation of anchorage-independent growth of transformed cells.
H. Fukazawa
,
Satoshi Mizuno
,
Y. Uehara
Analytical Biochemistry
1995
Corpus ID: 11326055
We developed a 96-well microplate assay to quantitate anchorage-independent growth of transformed cells. Wells of tissue culture…
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Highly Cited
1994
Highly Cited
1994
Correlation between immune and vascular activities of xanthenone acetic acid antitumor agents.
L. Zwi
,
Bruce C. Baguley
,
Gavin Jb
,
Wilson Wr
Oncology Research
1994
Corpus ID: 46643104
To determine whether xanthenone acetic acid (XAA) analogues of flavone acetic acid (FAA) have similar ischemic and nonischemic…
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Highly Cited
1994
Highly Cited
1994
Rapid acquisition of multicellular drug resistance after a single exposure of mammary tumor cells to antitumor alkylating agents.
Charles H. Graham
,
Hiroaki Kobayashi
,
Krystyne S. Stankiewicz
,
S. Man
,
Sean J. Kapitain
,
R. Kerbel
Journal of the National Cancer Institute
1994
Corpus ID: 23730817
BACKGROUND Clinical drug resistance is either intrinsic (de novo) or often acquired rapidly in conjunction with chemotherapy. By…
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Highly Cited
1991
Highly Cited
1991
Encapsulated multicellular spheroids of rat hepatocytes produce albumin and urea in a spouted bed circulating culture system.
Hiroyuki Takabatake
,
Norio Koide
,
Takao Tsuji
Artificial Organs
1991
Corpus ID: 32952763
Multicellular spheroids are spherical cell-aggregates that retain tridimensional architecture and tissue-specific functions. For…
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Highly Cited
1991
Highly Cited
1991
High albumin production by multicellular spheroids of adult rat hepatocytes formed in the pores of polyurethane foam
T. Matsushita
,
H. Ijima
,
N. Koide
,
K. Funatsu
Applied Microbiology and Biotechnology
1991
Corpus ID: 10192638
SummaryAdult rat hepatocytes formed spherical multicellular aggregates (spheroids) when they were cultured in the pores of…
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Highly Cited
1990
Highly Cited
1990
Smooth muscle-derived factor stimulates mobility of human tumor cells.
Eliot M. Rosen
,
L. Meromsky
,
E. Setter
,
Vinter Dw
,
Goldberg Id
Invasion and Metastasis
1990
Corpus ID: 23865578
Invasion of normal tissues is a complex process which requires active locomotion of malignant cells. Recent studies have…
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Highly Cited
1986
Highly Cited
1986
Proliferative and clonogenic heterogeneity of cells from EMT6/Ro multicellular spheroids induced by the glucose and oxygen supply.
J. Freyer
,
R. Sutherland
Cancer Research
1986
Corpus ID: 14057478
The culture of EMT6/Ro multicellular tumor spheroids in a 20-fold range of glucose concentrations and a 4-fold range of oxygen…
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Highly Cited
1985
Highly Cited
1985
The radiobiology of human neuroblastoma.
J. Deacon
,
P. A. Wilson
,
M. Peckham
Radiotherapy and Oncology
1985
Corpus ID: 4187287
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