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Spectrin

Known as: Spectrin [Chemical/Ingredient], Spectrins 
A high molecular weight (220-250 kDa) water-soluble protein which can be extracted from erythrocyte ghosts in low ionic strength buffers. The protein… 
National Institutes of Health

Related topics

Related topics

24 relations

Broader (1)

Cytoskeletal Proteins

Narrower (15)

GTRAP41 protein, ratPLEKHG4 protein, humanSPHEROCYTOSIS, TYPE 3 (disorder)SPTBN1 protein, human
Process of secretionagonistsantagonists & inhibitorsaspects of radiation effects

Papers overview

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Highly Cited
2009
Highly Cited
2009
Localization and Structure of the Ankyrin-binding Site on β2-Spectrin*
Spectrins are tetrameric actin-cross-linking proteins that form an elastic network, termed the membrane skeleton, on the… 
Review
2006
Review
2006
Glial regulation of the axonal membrane at nodes of Ranvier
2006
2006
Thermal stabilities of brain spectrin and the constituent repeats of subunits.
The different genes that encode mammalian spectrins give rise to proteins differing in their apparent stiffness. To explore this… 
Review
2005
Review
2005
Kalirin: A Dual Rho Guanine Nucleotide Exchange Factor That Is So Much More Than the Sum of Its Many Parts
A large number of Rho guanine nucleotide exchange factors (GEFs) and Rho GTPase activating proteins (GAPs) are used in the CNS to… 
Highly Cited
1993
Highly Cited
1993
The 270 kDa splice variant of erythrocyte beta-spectrin (beta I sigma 2) segregates in vivo and in vitro to specific domains of cerebellar neurons.
Spectrin isoforms arise from four distinct genes, three of which generate multiple alternative transcripts. With no biochemical… 
Highly Cited
1993
Highly Cited
1993
Localization of dystrophin and beta-spectrin in vacuolar myopathies.
We examined the expression of the cytoskeletal proteins dystrophin and beta-spectrin on vacuolar boundaries in vacuolar… 
1988
1988
Spectrin-like proteins in the paraflagellar rod structure of Trypanosoma brucei.
A polyclonal, monospecific rabbit antibody to human erythrocyte spectrins cross-reacted with two sets of proteins (a doublet of… 
1985
1985
Remarkable homology among the internal repeats of erythroid and nonerythroid spectrin.
A cDNA clone for nonerythroid alpha-spectrin was identified by direct immunological screening of a chicken smooth muscle cDNA… 
Highly Cited
1984
Highly Cited
1984
Comparison of spectrin isolated from erythroid and non-erythroid sources.
Spectrin from erythrocytes and two other tissues (brain and intestine) were isolated from two distant species, pig and chicken… 
Highly Cited
1983
Highly Cited
1983
Molecular and functional changes in spectrin from patients with hereditary pyropoikilocytosis.
The structural and functional properties of spectrin from normal and hereditary pyropoikilocytosis (HPP) donors from the two… 
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