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Spectrin

Known as: Spectrin [Chemical/Ingredient], Spectrins 
A high molecular weight (220-250 kDa) water-soluble protein which can be extracted from erythrocyte ghosts in low ionic strength buffers. The protein… 
National Institutes of Health

Related topics

Related topics

24 relations

Broader (1)

Cytoskeletal Proteins

Narrower (15)

GTRAP41 protein, ratPLEKHG4 protein, humanSPHEROCYTOSIS, TYPE 3 (disorder)SPTBN1 protein, human
Process of secretionagonistsantagonists & inhibitorsaspects of radiation effects

Papers overview

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2010
2010
Reduced expression of the membrane skeleton protein beta1-spectrin (SPTBN1) is associated with worsened prognosis in pancreatic cancer.
Spectrins are members of the superfamily of F-actin cross linking proteins that are important as scaffolding proteins for protein… 
Highly Cited
2009
Highly Cited
2009
Localization and Structure of the Ankyrin-binding Site on β2-Spectrin*
Spectrins are tetrameric actin-cross-linking proteins that form an elastic network, termed the membrane skeleton, on the… 
Review
2006
Review
2006
Glial regulation of the axonal membrane at nodes of Ranvier
1994
1994
A partial structural repeat forms the heterodimer self-association site of all beta-spectrins.
The self-polymerization of alpha beta-spectrin heterodimers to form tetramers and higher oligomers is central to its role as a… 
Highly Cited
1993
Highly Cited
1993
The 270 kDa splice variant of erythrocyte beta-spectrin (beta I sigma 2) segregates in vivo and in vitro to specific domains of cerebellar neurons.
Spectrin isoforms arise from four distinct genes, three of which generate multiple alternative transcripts. With no biochemical… 
1992
1992
Characterization of calcium binding to spectrins.
Calcium binding to brain and erythrocyte spectrins was studied at physiological ionic strength by a calcium overlay assay and… 
Review
1990
Review
1990
Contractile Proteins in Drosophila Development a
In summary, we have used a multidisciplinary approach to the analysis of actomyosin-based motility during Drosophila… 
1988
1988
Spectrin-like proteins in the paraflagellar rod structure of Trypanosoma brucei.
A polyclonal, monospecific rabbit antibody to human erythrocyte spectrins cross-reacted with two sets of proteins (a doublet of… 
Highly Cited
1984
Highly Cited
1984
Comparison of spectrin isolated from erythroid and non-erythroid sources.
Spectrin from erythrocytes and two other tissues (brain and intestine) were isolated from two distant species, pig and chicken… 
Highly Cited
1983
Highly Cited
1983
Molecular and functional changes in spectrin from patients with hereditary pyropoikilocytosis.
The structural and functional properties of spectrin from normal and hereditary pyropoikilocytosis (HPP) donors from the two… 
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