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Spectrin

Known as: Spectrin [Chemical/Ingredient], Spectrins 
A high molecular weight (220-250 kDa) water-soluble protein which can be extracted from erythrocyte ghosts in low ionic strength buffers. The protein… 
National Institutes of Health

Related topics

Related topics

24 relations

Broader (1)

Cytoskeletal Proteins

Narrower (15)

GTRAP41 protein, ratPLEKHG4 protein, humanSPHEROCYTOSIS, TYPE 3 (disorder)SPTBN1 protein, human
Process of secretionagonistsantagonists & inhibitorsaspects of radiation effects

Papers overview

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Highly Cited
2015
Highly Cited
2015
The Spectrin cytoskeleton regulates the Hippo signalling pathway
The Spectrin cytoskeleton is known to be polarised in epithelial cells, yet its role remains poorly understood. Here, we show… 
Review
2011
Review
2011
Spectrin-based skeleton as an actor in cell signaling
This review focuses on the recent advances in functions of spectrins in non-erythroid cells. We discuss new data concerning the… 
Highly Cited
2010
Highly Cited
2010
Metabolic remodeling of the human red blood cell membrane
The remarkable deformability of the human red blood cell (RBC) results from the coupled dynamic response of the phospholipid… 
Highly Cited
2010
Highly Cited
2010
Flotillin microdomains interact with the cortical cytoskeleton to control uropod formation and neutrophil recruitment
The association between flotillin microdomains and the cortical cytoskeleton controls myosin IIa activation and neutrophil… 
Review
2007
Review
2007
Plakins in development and disease.
Highly Cited
2005
Highly Cited
2005
Cell junction-associated proteins IQGAP1, MAGI-2, CASK, spectrins, and alpha-actinin are components of the nephrin multiprotein complex.
Nephrin is a cell surface receptor of the Ig superfamily that localizes to slit diaphragms, the specialized junctions between the… 
Highly Cited
2004
Highly Cited
2004
βIV Spectrins Are Essential for Membrane Stability and the Molecular Organization of Nodes of Ranvier
High densities of sodium channels at nodes of Ranvier permit action potential conduction and depend on βIV spectrins, a family of… 
Highly Cited
1989
Highly Cited
1989
The complete sequence of Drosophila alpha-spectrin: conservation of structural domains between alpha-spectrins and alpha-actinin
We report the complete sequence of Drosophila alpha-spectrin and show that it is similar to vertebrate nonerythroid spectrins. As… 
Highly Cited
1981
Highly Cited
1981
Self-assembly of spectrin oligomers in vitro: a basis for a dynamic cytoskeleton
Purified human erythrocyte spectrin is able to form large oligomeric species without the collaboration of any other proteins… 
Highly Cited
1979
Highly Cited
1979
The lateral distribution of intramembrane particles in the erythrocyte membrane and recombinant vesicles.
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