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Somatic Cell Genetics

Various methods for gene function studies that rely on the use of cells in culture.
National Institutes of Health

Papers overview

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Highly Cited
2015
Highly Cited
2015
The CRISPR/Cas9 system has revolutionized mammalian somatic cell genetics. Genome-wide functional screens using CRISPR/Cas9… Expand
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Highly Cited
2001
Highly Cited
2001
Global patterns of human DNA sequence variation (haplotypes) defined by common single nucleotide polymorphisms (SNPs) have… Expand
Highly Cited
1987
Highly Cited
1987
Embryonal stem (ES) cell lines, established in culture from peri-implantation mouse blastocysts1–3, can colonize both the somatic… Expand
Highly Cited
1984
Highly Cited
1984
Cell culture and somatic cell genetics of plants , Cell culture and somatic cell genetics of plants… Expand
Review
1981
Review
1981
Mammalian gene mapping techniques are now sufficiently advanced to contribute significantly to prenatal diagnosis and to human… Expand
Highly Cited
1980
Highly Cited
1980
Plant regeneration from totipotent cultured cells or protoplasts is a prerequisite for the often proposed genetic modification of… Expand
Highly Cited
1978
Highly Cited
1978
Antibody-secreting hybrid cells have been derived from a fusion between mouse myeloma cells and spleen cells from a mouse… Expand
Highly Cited
1973
Highly Cited
1973
Techniques for the study of somatic cell genetics, and particularly those involving the expression of enzyme markers in hybrid… Expand
Highly Cited
1973
Highly Cited
1973
SOMATIC cell populations can be used for genetic analysis because of the occurrence of parasexual events1. Genetically dilferent… Expand
Review
1972
Review
1972
  • F. Ruddle
  • Advances in human genetics
  • 1972
  • Corpus ID: 12595704
It is my aim in this article to review current progress in somatic cell genetics. Somatic cell genetics, although a relatively… Expand