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Somatic Cell Genetics

Various methods for gene function studies that rely on the use of cells in culture.
National Institutes of Health

Papers overview

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Review
1995
Review
1995
The potential of somatic hybridization in crop breeding
SummaryIn recent years, the rapid development of somatic cell genetics has made possible the transfer of alien genes over wide… 
Highly Cited
1984
Highly Cited
1984
Gene mapping in the rat by mouse-rat somatic cell hybridization: synteny of the albumin and alpha-fetoprotein genes and assignment to chromosome 14.
The methods of somatic cell genetics and molecular hybridization were applied to a panel of mouse X rat hepatocyte hybrids… 
Highly Cited
1983
Highly Cited
1983
X-ray-sensitive mutants of Chinese hamster ovary cell line. Isolation and cross-sensitivity to other DNA-damaging agents.
Highly Cited
1983
Highly Cited
1983
Somatic cell genetics and gene families.
The utility of somatic cell genetic analysis for the chromosomal localization of genes in mammals is well established. With the… 
Review
1981
Review
1981
A new era in mammalian gene mapping: somatic cell genetics and recombinant DNA methodologies
Mammalian gene mapping techniques are now sufficiently advanced to contribute significantly to prenatal diagnosis and to human… 
Highly Cited
1980
Highly Cited
1980
Somatic embryogenesis from Sorghum bicolor leaves
Plant regeneration from totipotent cultured cells or protoplasts is a prerequisite for the often proposed genetic modification of… 
Highly Cited
1974
Highly Cited
1974
The somatic cell genetics of human interferon: assignment of human interferon loci to chromosomes 2 and 5.
A total of 40 mouse-human cell hybrids were induced with poly(I).poly(C) and with Newcastle disease virus. Ten hybrid clones… 
Highly Cited
1973
Highly Cited
1973
Linkage Analysis in Man by Somatic Cell Genetics
Techniques for the study of somatic cell genetics, and particularly those involving the expression of enzyme markers in hybrid… 
Highly Cited
1973
Highly Cited
1973
Assignment of nucleoside phosphorylase to D-14 and localization of X-linked loci in man by somatic cell genetics.
SOMATIC cell populations can be used for genetic analysis because of the occurrence of parasexual events1. Genetically dilferent… 
Review
1972
Review
1972
Linkage analysis using somatic cell hybrids.
It is my aim in this article to review current progress in somatic cell genetics. Somatic cell genetics, although a relatively… 
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