Somatic Cell Genetics

Various methods for gene function studies that rely on the use of cells in culture.
National Institutes of Health

Topic mentions per year

Topic mentions per year

1962-2015
024619622015

Papers overview

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Highly Cited
2015
Highly Cited
2015
The CRISPR/Cas9 system has revolutionized mammalian somatic cell genetics. Genome-wide functional screens using CRISPR/Cas9… (More)
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2002
2002
In recent years, a growing number of mammalian genes have been shown to undergo alternative splicing in response to extracellular… (More)
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Highly Cited
2001
Highly Cited
2001
Global patterns of human DNA sequence variation (haplotypes) defined by common single nucleotide polymorphisms (SNPs) have… (More)
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Highly Cited
2000
Highly Cited
2000
Control of mRNA stability is critical for expression of short-lived transcripts from cytokines and proto-oncogenes. Regulation… (More)
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Highly Cited
1987
Highly Cited
1987
Embryonal stem (ES) cell lines, established in culture from peri-implantation mouse blastocysts1–3, can colonize both the somatic… (More)
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1984
1984
The methods of somatic cell genetics and molecular hybridization were applied to a panel of mouse X rat hepatocyte hybrids… (More)
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1983
1983
The utility of somatic cell genetic analysis for the chromosomal localization of genes in mammals is well established. With the… (More)
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1980
1980
Plant regeneration from totipotent cultured cells or protoplasts is a prerequisite for the often proposed genetic modification of… (More)
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Highly Cited
1978
Highly Cited
1978
Antibody-secreting hybrid cells have been derived from a fusion between mouse myeloma cells and spleen cells from a mouse… (More)
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1973
1973
Techniques for the study of somatic cell genetics, and particularly those involving the expression of enzyme markers in hybrid… (More)
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