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Solute Carrier Family 22 Member 1

Known as: Organic Cation Transporter 1, SLC22A1, hOCT1 
Solute carrier family 22 member 1 (554 aa, ~61 kDa) is encoded by the human SLC22A1 gene. This protein is involved in bidirectional cation transport.
National Institutes of Health

Papers overview

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2018
2018
Background Imatinib is actively transported into cells by the organic cation transporter (OCT1), encoded by SLC22A1. As a result… 
2013
2013
Objective: To study quantitative expression of the genes MDR1 and hOCT1 in 30 patients with chronic myeloid leukemia (CML) and 27… 
2012
2012
Imatinib is a substrate for hOCT1 (SLC22A1) and inhibitors of this influx transporter, such as amantadine and prazosin, have… 
2009
2009
The platinum antitumor drug oxaliplatin, [Pt(DACH)(oxalate)] (Figure 1A), is frequently used in the treatment of colon and… 
2008
2008
Cellular membrane affinity chromatography (CMAC) columns have been created through the immobilization of cellular membrane… 
2004
2004
Category: Genotype PharmGKB Submission Number: PS203001 Date of Submission: June 16, 2003 Project: Pharmacogenetics of… 
2002
2002
It is well established that polymorphic genetic variations in some drug-metabolizing enzymes can dramatically affect the handling…