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SLC22A4 gene

Known as: SLC22A4, ORGANIC CATION TRANSPORTER 1, MGC34546 
National Institutes of Health

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SLC22A1 gene

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Solute Carrier Family 22 Member 1

Papers overview

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2012
2012
Crohn's disease in Caucasians and African Americans, as defined by clinical predictors and single nucleotide polymorphisms.
2010
2010
Increased expression of hepatic organic cation transporter 1 and hepatic distribution of metformin in high-fat diet-induced obese mice.
Although the effect of obesity on drug disposition remains an important issue for clinicians, little is known about the effects… 
2010
2010
Genetic variants of STAT4 associated with rheumatoid arthritis in persons of Asian and European ancestry do not replicate in African Americans
Rheumatoid arthritis (RA) was recently genetically associated with signal transducer and activator of transcription 4 ( STAT4… 
2009
2009
Peroxisome proliferator-activated receptor alpha and enzymes of carnitine biosynthesis in the liver are down-regulated during lactation in rats.
2006
2006
Prevalence of SLC22A4, SLC22A5 and CARD15 gene mutations in Hungarian pediatric patients with Crohn's disease.
AIM To investigate the frequency of the common NOD2/CARD15 susceptibility variants and two functional polymorphisms of OCTN… 
2006
2006
SLC22A4, RUNX1, and SUMO4 polymorphisms are not associated with rheumatoid arthritis: a case-control study in a Spanish population.
OBJECTIVE To replicate the association reported in Japanese individuals of functional SLC22A4 and RUNX1 polymorphisms with… 
2005
2005
SLC22A4 polymorphisms implicated in rheumatoid arthritis and Crohn's disease are not associated with rheumatoid arthritis in a Canadian Caucasian population.
OBJECTIVE Single-nucleotide polymorphisms (SNPs) in the SLC22A4 gene encoding the organic cation transporter OCTN1 have been… 
2005
2005
Failure to confirm association between SLC22A4 polymorphism and rheumatoid arthritis in a Japanese population.
2004
2004
Functional characterization of human organic cation transporter OCTN1 single nucleotide polymorphisms in the Japanese population.
The organic cation transporter OCTN1 (SLC22A4) is expressed ubiquitously, with strong expression in kidney, trachea, bone marrow… 
2003
2003
Functional Domains in the Carnitine Transporter OCTN2, Defective in Primary Carnitine Deficiency*
Primary carnitine deficiency is an autosomal recessive disorder of fatty acid oxidation characterized by hypoketotic hypoglycemia… 
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