Soluble ErbB-1

Known as: sEGFR, sErbB-1, EGFR-ECD 
Soluble epidermal growth factor receptor is encoded by the human EGFR gene. This protein may be involved in the regulation of epidermal growth factor… (More)
National Institutes of Health

Papers overview

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2011
2011
AIMS Members of the epidermal growth factor receptor (EGFR) family represent validated targets for anti-cancer therapy and EGFR… (More)
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Highly Cited
2009
Highly Cited
2009
This trial was conducted to assess the efficacy and safety of sorafenib in patients with metastatic breast cancer. In this… (More)
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2008
2008
In this study, we show that liquid chromatography coupled with tandem mass spectrometry provides a sensitive, specific, and… (More)
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Highly Cited
2005
Highly Cited
2005
Recent structural studies of epidermal growth factor receptor (EGFR) family extracellular regions have identified an unexpected… (More)
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Highly Cited
2003
Highly Cited
2003
Epidermal growth factor (EGF) receptor is the prototype of the ErbB (HER) family receptor tyrosine kinases (RTKs), which regulate… (More)
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Highly Cited
2003
Highly Cited
2003
During inflammatory skin disorders such as psoriasis, atopic dermatitis, and allergic contact dermatitis, epidermal keratinocytes… (More)
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2002
2002
Despite improved diagnostic accuracy, differentiation of dementia with Lewy bodies (DLB) and Alzheimer's disease (AD) on the… (More)
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Highly Cited
2002
Highly Cited
2002
We report the crystal structure, at 2.5 A resolution, of a truncated human EGFR ectodomain bound to TGFalpha. TGFalpha interacts… (More)
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2000
2000
To elucidate a role(s) of Asn-linked sugar chain(s) in the function of epidermal growth factor receptor (EGFR), a series of the… (More)
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2000
2000
The extracellular domain of human EGF receptor (sEGFR) produced by CHO cells has been used in various biophysical studies to… (More)
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