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Sodium-Glucose Transporter 2

Known as: SGLT2 Protein, SLC5A2 Protein, Sodium-Glucose Transporter 2 [Chemical/Ingredient] 
A sodium-glucose transporter that is expressed in the luminal membrane of the PROXIMAL KIDNEY TUBULES.
National Institutes of Health

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In BloodProcess of secretionSLC5A2 geneagonists

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SLC5A2 protein, human

Papers overview

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2020
2020
Interindividual Heterogeneity of SGLT2 Expression and Function in Human Pancreatic Islets
Studies implicating sodium–glucose cotransporter 2 (SGLT2) inhibitors in glucagon secretion by pancreatic α-cells reported… 
2018
2018
Validation of sodium/glucose cotransporter proteins in human brain as a potential marker for temporal narrowing of the trauma formation
In many forensic cases, the existence of a traumatic brain injury (TBI) is an essential factor, and the determination of the… 
Review
2016
Review
2016
Diabetic ketoacidosis, sodium glucose transporter-2 inhibitors and the kidney.
2015
2015
Sodium glucose transporter 2 (SGLT2) inhibition and ketogenesis
Sodium glucose transporter 2 (SGLT2) inhibitors are a recently developed class of drug that have been approved for use in type 2… 
2014
2014
Pharmacokinetic and pharmacodynamic study of ipragliflozin in Japanese patients with type 2 diabetes mellitus: a randomized, double-blind, placebo-controlled study.
2013
2013
Hypoxia-inducible Factor-1α (HIF-1α) Protein Diminishes Sodium Glucose Transport 1 (SGLT1) and SGLT2 Protein Expression in Renal Epithelial Tubular Cells (LLC-PK1) under Hypoxia*
Background: Hypoxia regulates the transport systems expression in kidney cells. Results: Expression of SGLT1 and SGLT2 is… 
Highly Cited
2012
Highly Cited
2012
Expression of Na+-D-glucose cotransporter SGLT2 in rodents is kidney-specific and exhibits sex and species differences.
With a novel antibody against the rat Na(+)-D-glucose cotransporter SGLT2 (rSGLT2-Ab), which does not cross-react with rSGLT1 or… 
Highly Cited
2012
Highly Cited
2012
Remogliflozin Etabonate, a Selective Inhibitor of the Sodium-Glucose Transporter 2, Improves Serum Glucose Profiles in Type 1 Diabetes
OBJECTIVE Remogliflozin etabonate (RE), an inhibitor of the sodium-glucose transporter 2, improves glucose profiles in type 2… 
2010
2010
C-Aryl glycoside inhibitors of SGLT2: Exploration of sugar modifications including C-5 spirocyclization.
2004
2004
High Glucose Levels Down-Regulate Glucose Transporter Expression That Correlates With Increased Oxidative Stress in Placental Trophoblast Cells IN Vitro
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