SLC5A2 gene

Known as: Solute Carrier Family 5 (Sodium/Glucose Cotransporter), Member 2 Gene, SGLT2, SODIUM-GLUCOSE COTRANSPORTER, KIDNEY LOW AFFINITY 
This gene is involved in the transport of both glucose and sodium.
National Institutes of Health

Papers overview

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Review
2016
Review
2016
Healthy kidneys filter ∼160 g/day of glucose (∼30% of daily energy intake) under euglycaemic conditions. To prevent valuable… (More)
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Review
2015
Review
2015
CONTEXT Sodium glucose cotransporter 2 (SGLT2) inhibitors are antidiabetic drugs that increase urinary excretion of glucose… (More)
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Highly Cited
2015
Highly Cited
2015
OBJECTIVE Insulin adjustments to maintain glycemic control in individuals with type 1 diabetes often lead to wide glucose… (More)
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Review
2014
Review
2014
Inhibitors of sodium–glucose co-transporter type 2 (SGLT2) are proposed as a novel approach for the management of type 2 diabetes… (More)
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Highly Cited
2013
Highly Cited
2013
AIM This Phase IIb, randomized, double-blind, placebo-controlled trial evaluated the efficacy, safety, tolerability and… (More)
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Highly Cited
2012
Highly Cited
2012
OBJECTIVE To examine the safety and efficacy of dapagliflozin, a sodium-glucose cotransporter-2 inhibitor, added on to… (More)
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Highly Cited
2009
Highly Cited
2009
Dapagliflozin selectively inhibits renal glucose reabsorption by inhibiting sodium-glucose cotransporter-2 (SGLT2). It was… (More)
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Highly Cited
2008
Highly Cited
2008
OBJECTIVE The inhibition of gut and renal sodium-glucose cotransporters (SGLTs) has been proposed as a novel therapeutic approach… (More)
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Highly Cited
2008
Highly Cited
2008
The low-affinity sodium glucose cotransporter (SGLT2) plays an important role in renal glucose reabsorption and is a remarkable… (More)
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Highly Cited
2007
Highly Cited
2007
The low-affinity sodium glucose cotransporter (SGLT2), which is expressed specifically in the kidney, plays a major role in renal… (More)
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