Dysregulation of the Peripheral and Adipose Tissue Endocannabinoid System in Human Abdominal Obesity
The endocannabinoid system has been suspected to contribute to the association of visceral fat accumulation with metabolic diseases. We determined whether circulating endocannabinoids are related to… Expand
Orthostatic intolerance and tachycardia associated with norepinephrine-transporter deficiency.
- J. Shannon, N. Flattem, +5 authors D. Robertson
- The New England journal of medicine
- 24 February 2000
BACKGROUND Orthostatic intolerance is a syndrome characterized by lightheadedness, fatigue, altered mentation, and syncope and associated with postural tachycardia and plasma norepinephrine… Expand
The pressor response to water drinking in humans : a sympathetic reflex?
BACKGROUND Water drinking increases blood pressure profoundly in patients with autonomic failure and substantially in older control subjects. The mechanism that mediates this response is not known.… Expand
Retinol-Binding Protein 4 in Human Obesity
Studies in mice suggest that adipocytes serve as glucose sensors and regulate systemic glucose metabolism through release of serum retinol-binding protein 4 (RBP4). This model has not been validated… Expand
Influences of Normobaric Hypoxia Training on Physical Fitness and Metabolic Risk Markers in Overweight to Obese Subjects
Previous studies suggested that hypoxia and exercise may have a synergistic effect on cardiovascular and metabolic risk factors. We conducted a single blind study in overweight to obese subjects to… Expand
The Molecular and Cellular Identity of Peripheral Osmoreceptors
In mammals, the osmolality of the extracellular fluid (ECF) is highly stable despite radical changes in salt/water intake and excretion. Afferent systems are required to detect hypo- or hyperosmotic… Expand
Interaction of Carbon Dioxide and Sympathetic Nervous System Activity in the Regulation of Cerebral Perfusion in Humans
Recent studies suggest that activation of the sympathetic nervous system either directly or indirectly influences cerebrovascular tone in humans even within the autoregulatory range. In 6 healthy… Expand
Water drinking as a treatment for orthostatic syndromes.
PURPOSE Water drinking increases blood pressure in a substantial proportion of patients who have severe orthostatic hypotension due to autonomic failure. We tested the hypothesis that water drinking… Expand
Women Have Lower Tonic Autonomic Support of Arterial Blood Pressure and Less Effective Baroreflex Buffering Than Men
- D. D. Christou, P. Jones, J. Jordan, A. Diedrich, D. Robertson, D. Seals
- 1 February 2005
Background—Short-term and tonic regulation of arterial blood pressure (BP) differ in premenopausal women and men of similar age. The autonomic nervous system (ANS) plays a critical role in BP… Expand
Autonomic cardiovascular and respiratory control during prolonged spaceflights aboard the International Space Station.
- R. Baevsky, V. Baranov, +6 authors J. Tank
- Medicine, Chemistry
- Journal of applied physiology
- 1 July 2007
Impaired autonomic control represents a cardiovascular risk factor during long-term spaceflight. Little has been reported on blood pressure (BP), heart rate (HR), and heart rate variability (HRV)… Expand