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Sodium Butyrate

Known as: Butyrate sodium, Butyric Acid, Sodium Salt, Sodium butanoate 
The sodium salt of butyrate with potential antineoplastic activity. Butyrate, a short chain fatty acid, competitively binds to the zinc sites of… 
National Institutes of Health

Related topics

Related topics

4 relations

Broader (3)

Butyric AcidButyric Acidsbutyrate
NCIt Antineoplastic Agent Terminology

Papers overview

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Highly Cited
2009
Highly Cited
2009
Butyrate Improves Insulin Sensitivity and Increases Energy Expenditure in Mice
OBJECTIVE We examined the role of butyric acid, a short-chain fatty acid formed by fermentation in the large intestine, in the… 
Review
2003
Review
2003
Inhibition of histone deacetylase activity by butyrate.
This article reviews the effects of the short-chain fatty acid butyrate on histone deacetylase (HDAC) activity. Sodium butyrate… 
Highly Cited
2003
Highly Cited
2003
Histone Deacetylase Inhibition by Sodium Butyrate Chemotherapy Ameliorates the Neurodegenerative Phenotype in Huntington's Disease Mice
The precise cause of neuronal death in Huntington's disease (HD) is unknown. Although no single specific protein-protein… 
Highly Cited
2000
Highly Cited
2000
Anti‐inflammatory effects of sodium butyrate on human monocytes: potent inhibition of IL‐12 and up‐regulation of IL‐10 production
Cytokines are critical in regulating unresponsiveness versus immunity towards enteric antigens derived from the intestinal flora… 
Highly Cited
1999
Highly Cited
1999
Deconstructing a Disease: RAR, Its Fusion Partners, and Their Roles in the Pathogenesis of Acute Promyelocytic Leukemia
I N THE LATE 1980s and early 1990s, the elucidation of the molecular basis of acute promyelocytic leukemia (APL) emerged as a… 
Highly Cited
1993
Highly Cited
1993
Sodium butyrate induces apoptosis in human colonic tumour cell lines in a p53‐independent pathway: Implications for the possible role of dietary fibre in the prevention of large‐bowel cancer
The purpose of this study was to determine whether cultured colonic adenoma and carcinoma cells undergo apoptosis (programmed… 
Highly Cited
1992
Highly Cited
1992
Effect of butyrate enemas on the colonic mucosa in distal ulcerative colitis.
Highly Cited
1984
Highly Cited
1984
Emergence of permanently differentiated cell clones in a human colonic cancer cell line in culture after treatment with sodium butyrate.
The human colonic cancer cell line HT29 is undifferentiated in standard culture conditions (Dulbecco's medium:10% fetal bovine… 
Highly Cited
1978
Highly Cited
1978
Sodium butyrate inhibits histone deacetylation in cultured cells
Highly Cited
1978
Highly Cited
1978
The effect of sodium butyrate on histone modification
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