Small Inducible Cytokine A19

Known as: Exodus-3 Chemokine, Macrophage Inflammatory Protein 3 beta, Chemokine, CCL19 
A CC-type chemokine with specificity for CCR7 RECEPTORS. It has activity towards T LYMPHOCYTES and B LYMPHOCYTES.
National Institutes of Health

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CCL19 geneCCL19 wt AlleleIn BloodProcess of secretion
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CCL19 protein, human

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chemokine

Papers overview

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2008
2008
CD137 ligand reverse signaling has multiple functions in human dendritic cells during an adaptive immune response.
T cell activation via dendritic cells (DC) is an important step in the adaptive immune response, which requires DC maturation… (More)
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Highly Cited
2005
Highly Cited
2005
Plasmacytoid dendritic cells induce CD8+ regulatory T cells in human ovarian carcinoma.
To directly dissect the role of each immune component in human tumor immunopathogenesis, we have studied the interaction between… (More)
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Highly Cited
2001
Highly Cited
2001
Expression and regulation of chemokine receptors in human natural killer cells.
Using flow cytometric and RNase protection assays, this study examined the expression of chemokine receptors in nonactivated… (More)
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Highly Cited
2001
Highly Cited
2001
Expression of CCR-7, MIP-3beta, and Th-1 chemokines in type I IFN-induced monocyte-derived dendritic cells: importance for the rapid acquisition of potent migratory and functional activities.
The migration capability of dendritic cells (DCs) is regulated by their response to factors, namely chemokines, that characterize… (More)
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Highly Cited
2001
Highly Cited
2001
Neutrophils produce biologically active macrophage inflammatory protein-3alpha (MIP-3alpha)/CCL20 and MIP-3beta/CCL19.
Macrophage inflammatory protein-3alpha (MIP-3alpha)/CCL20 and MIP-3beta/CCL19 are members of the CC chemokine subfamily which… (More)
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Highly Cited
2000
Highly Cited
2000
The Role of Chemokines in the Microenvironmental Control of T versus B Cell Arrest in Peyer's Patch High Endothelial Venules
Chemokines have been hypothesized to contribute to the selectivity of lymphocyte trafficking not only as chemoattractants, but… (More)
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Highly Cited
1999
Highly Cited
1999
Macrophage Inflammatory Protein 3α Is Involved in the Constitutive Trafficking of Epidermal Langerhans Cells
Certain types of dendritic cells (DCs) appear in inflammatory lesions of various etiologies, whereas other DCs, e.g., Langerhans… (More)
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Highly Cited
1998
Highly Cited
1998
Selective Recruitment of Immature and Mature Dendritic Cells by Distinct Chemokines Expressed in Different Anatomic Sites
DCs (dendritic cells) function as sentinels of the immune system. They traffic from the blood to the tissues where, while… (More)
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Highly Cited
1998
Highly Cited
1998
6-C-kine (SLC), a Lymphocyte Adhesion-triggering Chemokine Expressed by High Endothelium, Is an Agonist for the MIP-3β Receptor CCR7
The beta chemokine known as 6-C-kine, secondary lymphoid-tissue chemokine (SLC), TCA4, or Exodus-2 (herein referred to as 6CK/SLC… (More)
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Highly Cited
1998
Highly Cited
1998
EBI1/CCR7 is a new member of dendritic cell chemokine receptor that is up-regulated upon maturation.
Dendritic cells (DC) that are stimulated with inflammatory mediators can maturate and migrate from nonlymphoid tissues to… (More)
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