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Voltage-gated L-type Ca2+ channels (LTCCs) containing a pore-forming alpha1D subunit (D-LTCCs) are expressed in neurons and… Expand This article focuses on the regional heterogeneity of the mammalian sinoatrial (SA) node in terms of cell morphology, pacemaker… Expand Group A streptococci are model extracellular gram-positive pathogens responsible for pharyngitis, impetigo, rheumatic fever, and… Expand BACKGROUND
In patients with heart failure, beta-blockade has improved morbidity and left-ventricular function, but the impact on… Expand We have isolated a cardiomyogenic cell line (CMG) from murine bone marrow stromal cells. Stromal cells were immortalized, treated… Expand In response to numerous pathologic stimuli, the myocardium undergoes a hypertrophic response characterized by increased… Expand Mutations in HERG cause an inherited cardiac arrhythmia, long QT syndrome (LQT). To define the function of HERG, we expressed the… Expand Major topics addressed in this review on cardiac pacemaking in the sinoatrial node are; 1) isolated pacemaker cells; 2) membrane… Expand In 57 normal subjects (age 20–60 years), we analyzed the spontaneous beat-to-beat oscillation in R-R interval during control… Expand Cardiac resuscitation after cardiac arrest or ventricular fibrillation has been limited by the need for open thoracotomy and… Expand