FAQ

Single molecule real time sequencing

Known as: SMRT sequencing 
Single molecule real time sequencing (SMRT) is a parallelized single molecule DNA sequencing method. Single molecule real time sequencing utilizes a… (More)
Wikipedia

Topic mentions per year

Topic mentions per year

2012-2018
051020122018

Related topics

Related topics

2 relations

Broader (1)

Bioinformatics
Whole genome sequencing

Related mentions per year

Related mentions per year

1964-2018
1960198020002020
Single molecule real time sequencing
Bioinformatics
Whole genome sequencing

Papers overview

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2017
2017
Profiling of Oral Microbiota in Early Childhood Caries Using Single-Molecule Real-Time Sequencing
Background: Alterations of oral microbiota are the main cause of the progression of caries. The goal of this study was to… (More)
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2017
2017
Comparative Genomic Analysis of Two Clonally Related Multidrug Resistant Mycobacterium tuberculosis by Single Molecule Real Time Sequencing
Background: Multidrug-resistant tuberculosis (MDR-TB) is posing a major threat to global TB control. In this study, we focused on… (More)
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2017
2017
MethSMRT: an integrative database for DNA N6-methyladenine and N4-methylcytosine generated by single-molecular real-time sequencing
DNA methylation is an important type of epigenetic modifications, where 5- methylcytosine (5mC), 6-methyadenine (6mA) and 4… (More)
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2016
2016
SimLoRD: Simulation of Long Read Data
MOTIVATION Third generation sequencing methods provide longer reads than second generation methods and have distinct error… (More)
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Review
2015
Review
2015
PacBio Sequencing and Its Applications
Single-molecule, real-time sequencing developed by Pacific BioSciences offers longer read lengths than the second-generation… (More)
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2015
2015
2SNV: Quasispecies reconstruction from PacBio reads
Pacific Biosciences (PacBio) sequencing is providing thousands of reads with the length up to 10,000 bases. In most cases this… (More)
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Review
2014
Review
2014
Preparation of next-generation DNA sequencing libraries from ultra-low amounts of input DNA: Application to single-molecule, real-time (SMRT) sequencing on the Pacific Biosciences RS II
We have developed and validated an amplification-free method for generating DNA sequencing libraries from very low amounts of… (More)
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Review
2014
Review
2014
Preparation of next-generation DNA sequencing libraries from ultra-low amounts of input DNA: Application to single-molecule, real-time (SMRT) sequencing on the Pacific Biosciences
We have developed and validated an amplification-free method for generating DNA sequencing libraries from very low amounts of… (More)
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Highly Cited
2013
Highly Cited
2013
The advantages of SMRT sequencing
Of the current next-generation sequencing technologies, SMRT sequencing is sometimes overlooked. However, attributes such as long… (More)
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2013
2013
Detecting DNA Modifications from SMRT Sequencing Data by Modeling Sequence Context Dependence of Polymerase Kinetic
DNA modifications such as methylation and DNA damage can play critical regulatory roles in biological systems. Single molecule… (More)
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