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SignalP Algorithm

Known as: SignalP 
An algorithm that predicts the presence and location of signal peptide cleavage sites in amino acid sequences. It incorporates a prediction of… 
National Institutes of Health

Papers overview

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Highly Cited
2015
Highly Cited
2015
Plastid proteome prediction for diatoms and other algae with secondary plastids of the red lineage
The plastids of ecologically and economically important algae from phyla such as stramenopiles, dinoflagellates and cryptophytes… 
Highly Cited
2012
Highly Cited
2012
Secretory signal peptide modification for optimized antibody-fragment expression-secretion in Leishmania tarentolae
BackgroundSecretory signal peptides (SPs) are well-known sequence motifs targeting proteins for translocation across the… 
Highly Cited
2011
Highly Cited
2011
DAMPD: a manually curated antimicrobial peptide database
The demand for antimicrobial peptides (AMPs) is rising because of the increased occurrence of pathogens that are tolerant or… 
Highly Cited
2009
Highly Cited
2009
Gene Profiling of Human Adipose Tissue During Evoked Inflammation In Vivo
OBJECTIVE Adipose inflammation plays a central role in obesity-related metabolic and cardiovascular complications. However, few… 
Review
2009
Review
2009
A comprehensive assessment of N-terminal signal peptides prediction methods
BackgroundAmino-terminal signal peptides (SPs) are short regions that guide the targeting of secretory proteins to the correct… 
Highly Cited
2008
Highly Cited
2008
High-performance signal peptide prediction based on sequence alignment techniques
UNLABELLED The accuracy of current signal peptide predictors is outstanding. The most successful predictors are based on neural… 
Highly Cited
2008
Highly Cited
2008
Cloning, expression and characterization of a thermotolerant endoglucanase from Syncephalastrum racemosum (BCC18080) in Pichia pastoris.
Highly Cited
2005
Highly Cited
2005
Evaluating eukaryotic secreted protein prediction
BackgroundImprovements in protein sequence annotation and an increase in the number of annotated protein databases has fueled… 
Highly Cited
2004
Highly Cited
2004
Signal sequence analysis of expressed sequence tags from the nematode Nippostrongylus brasiliensis and the evolution of secreted proteins in parasites
BackgroundParasitism is a highly successful mode of life and one that requires suites of gene adaptations to permit survival… 
Highly Cited
2000
Highly Cited
2000
A comparison of signal sequence prediction methods using a test set of signal peptides
We describe the creation of a test set containing secretory and non-secretory proteins. Five existing prediction programs for… 
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