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Showdomycin

Known as: 1H-Pyrrole-2,5-dione, 3-beta-D-ribofuranosyl-, Showdomycin [Chemical/Ingredient] 
3-beta-D-Ribofuranosylmaleimide. Antineoplastic antibiotic isolated from Streptomyces showdoensis. It is possibly active also as a sulfhydryl reagent… Expand
National Institutes of Health

Papers overview

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2017
2017
Nucleoside antibiotics are a large class of pharmaceutically relevant chemical entities, which exhibit a broad spectrum of… Expand
Highly Cited
2010
Highly Cited
2010
Showdomycin is a potent nucleoside antibiotic that displays a high structural similarity to uridine and pseudouridine. No… Expand
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Review
2009
Review
2009
While natural and synthetic N-nucleosides are vulnerable to enzymatic and acid-catalyzed hydrolysis of the nucleosidic bond… Expand
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1999
1999
Strategies for the synthesis of nucleosides that can provide either L or D isomers become more important as a result of the… Expand
Highly Cited
1981
Highly Cited
1981
The symmetric dimethyl esters derived from furan and dimethyl acetylenedicarboxylate was efficiently hydrolysed with pig liver… Expand
1974
1974
The chemical properties of showdomycin, a maleimide type antibiotic, were very similar to, but its biological properties rather… Expand
1972
1972
Abstract 1. 1. Two deoxycytidine transport systems were found in Escherichia coli K-12: on has a high affinity for deoxycytidine… Expand
1972
1972
  • T. Kalman
  • Biochemical and biophysical research…
  • 1972
  • Corpus ID: 30920644
Abstract Thymidylate synthetase of dichloromethotrexate resistant Lactobacillus casei was found to be rapidly and irreversibly… Expand
1968
1968
The metabolism and inhibitory effects of the carbon-linked nucleoside antibiotic showdomycin were investigated in cell-free… Expand
Highly Cited
1967
Highly Cited
1967
Showdomycin was first isolated from Streptomyces showdoensis by Nishimura and co-workers.1 It is a white crystalline antibotic of… Expand
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