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Short Transient Receptor Potential Channel 4

Known as: Trp-Related Protein 4, TrpC4, hTrp-4 
Short transient receptor potential channel 4 (977 aa, ~112 kDa) is encoded by the human TRPC4 gene. This protein plays a role in the transport of… 
National Institutes of Health

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14 relations
Ankyrin RepeatCellular MembraneIntegral Membrane ProteinsIon Channel

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2018
2018
Nicotine enhances store‑operated calcium entry by upregulating HIF‑1α and SOCC components in non‑small cell lung cancer cells.
Store‑operated calcium entry (SOCE) is critical for regulating the proliferation and metastasis of various cancer types. The… 
Review
2014
Review
2014
Kisspeptin and Gonadotropin-Releasing Hormone Neuronal Excitability: Molecular Mechanisms Driven by 17β-Estradiol
Kisspeptin is a neuropeptide that signals via a Gαq-coupled receptor, GPR54, in gonadotropin-releasing hormone (GnRH) neurons and… 
2011
2011
Vasoinhibins Prevent Bradykinin-Stimulated Endothelial Cell Proliferation by Inactivating eNOS via Reduction of both Intracellular Ca2+ Levels and eNOS Phosphorylation at Ser1179
Vasoinhibins, a family of antiangiogenic peptides derived from prolactin proteolysis, inhibit the vascular effects of several… 
2008
2008
Stim 1 and Orai 1 Mediate CRAC Currents and Store-Operated Calcium Entry Important for Endothelial Cell Proliferation
Recent breakthroughs in the store-operated calcium (Ca ) entry (SOCE) pathway have identified Stim1 as the endoplasmic reticulum… 
2007
2007
Microtubule Motors Regulate ISOC Activation Necessary to Increase Endothelial Cell Permeability*
Calcium store depletion activates multiple ion channels, including calcium-selective and nonselective channels. Endothelial cells… 
2007
2007
The sinoatrial node is still setting the pace 100 years after its discovery.
See related article, pages 1605–1614 The mammalian sinoatrial node, the pacemaker of the heart, was discovered 100 years ago in… 
2005
2005
Molecular cloning of TRPC3a, an N-terminally extended, store-operated variant of the human C3 transient receptor potential channel.
AK032317 is the GenBank accession no. of a full-length RIKEN mouse cDNA. It encodes a putative variant of the C3-type TRPC… 
Review
2005
Review
2005
Specific detection and semi-quantitative analysis of TRPC4 protein expression by antibodies
In mouse tissues two variants of the transient receptor potential (canonical) (TRPC) 4 protein are expressed: the “full-length… 
Review
2004
Review
2004
Control of TRPC and store-operated channels by protein kinase C.
TRPC channels are widely expressed among cells and are believed to play important roles in receptor-mediated Ca2+ signalling. We… 
Review
2004
Review
2004
TRPC4 and TRPC4-deficient mice.
TRP proteins, in most cases, provide localized Ca2+ increases for spatially defined signal transduction processes. They are… 
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