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Serine Palmitoyltransferase 1, Human

Known as: LCB 1, SPT 1, Long Chain Base Biosynthesis Protein 1 
Serine palmitoyltransferase 1 (473 aa, ~53 kDa) is encoded by the human SPTLC1 gene. This protein plays a role in the biosynthesis of sphingolipids.
National Institutes of Health

Papers overview

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2017
2017
Diabetes is considered a major public health problem affecting millions of individuals worldwide. Remarkably, scientific reports… 
2014
2014
Uneven crop stands result in a reduction in corn yield production. This study was conducted to determine the effect of delayed… 
2010
2010
The present work tested the hypothesis that a short-term dietary deficiency of magnesium (Mg) (21 days) in rats would result in… 
Highly Cited
2006
Highly Cited
2006
Aims/hypothesisMetformin has been shown to increase fatty acid oxidation, an effect mediated by AMP activated protein kinase… 
2006
2006
The total syntheses of tetrahydroxy-LCB 1, alpha-galactosyl ceramide 2, and 1,4-dideoxy-1,4-imino-L-ribitol 3 via D-allosamine… 
Highly Cited
1994
Highly Cited
1994
The first and committed step in synthesis of the ceramide moiety of sphingolipids is catalyzed by serine palmitoyltransferase (EC… 
Highly Cited
1988
Highly Cited
1988
Serine palmitoyltransferase (EC 2.3.1.50) catalyzes the condensation of L-serine and palmitoyl-CoA to yield 3-ketosphinganine in…