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Serine Palmitoyltransferase 1, Human

Known as: LCB 1, SPT 1, Long Chain Base Biosynthesis Protein 1 
Serine palmitoyltransferase 1 (473 aa, ~53 kDa) is encoded by the human SPTLC1 gene. This protein plays a role in the biosynthesis of sphingolipids.
National Institutes of Health

Papers overview

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2017
2017
Diabetes is considered a major public health problem affecting millions of individuals worldwide. Remarkably, scientific reports… Expand
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2014
2014
Uneven crop stands result in a reduction in corn yield production. This study was conducted to determine the effect of delayed… Expand
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2010
2010
The present work tested the hypothesis that a short-term dietary deficiency of magnesium (Mg) (21 days) in rats would result in… Expand
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2006
2006
Aims/hypothesisMetformin has been shown to increase fatty acid oxidation, an effect mediated by AMP activated protein kinase… Expand
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2006
2006
The total syntheses of tetrahydroxy-LCB 1, alpha-galactosyl ceramide 2, and 1,4-dideoxy-1,4-imino-L-ribitol 3 via D-allosamine… Expand
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Highly Cited
1994
Highly Cited
1994
The first and committed step in synthesis of the ceramide moiety of sphingolipids is catalyzed by serine palmitoyltransferase (EC… Expand
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1988
1988
Serine palmitoyltransferase (EC 2.3.1.50) catalyzes the condensation of L-serine and palmitoyl-CoA to yield 3-ketosphinganine in… Expand
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