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serine palmitoyltransferase

Known as: Palmitoyltransferase, Serine, Palmitoyl-Coenzyme A-L-Serine C-Palmitoyltransferase (Decarboxylating), Serine C Palmitoyltransferase 
A key enzyme in SPHINGOLIPIDS biosynthesis, this enzyme catalyzes the pyridoxal-5'-phosphate-dependent condensation of L-SERINE and PALMITOYL… 
National Institutes of Health

Papers overview

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Highly Cited
2011
Highly Cited
2011
The contribution of mutations in amyloid precursor protein (APP) and presenilin (PSEN) to familial Alzheimer's disease (AD) is… 
Highly Cited
2009
Highly Cited
2009
Serine palmitoyltransferase (SPT) catalyzes the first committed step in sphingolipid biosynthesis. In yeast, SPT is composed of a… 
Highly Cited
2009
Highly Cited
2009
The enzyme serine palmitoyltransferase (SPT) catalyzes the rate-limiting step in the de novo synthesis of sphingolipids… 
Highly Cited
2006
Highly Cited
2006
Serine-palmitoyltransferase (SPT) catalyzes the rate-limiting step of the de novo synthesis of sphingolipids. SPT is considered… 
Review
2003
Review
2003
  • K. Hanada
  • Biochimica et biophysica acta
  • 2003
  • Corpus ID: 23146294
Highly Cited
2001
Highly Cited
2001
Hereditary sensory neuropathy type I (HSN1) is the most common hereditary disorder of peripheral sensory neurons. HSN1 is an… 
Highly Cited
2000
Highly Cited
2000
The de novo pathway of sphingolipid synthesis has been identified recently as a novel means of generating ceramide during… 
Highly Cited
1998
Highly Cited
1998
We reported that the lipoapoptosis of beta-cells observed in fat-laden islets of obese fa/fa Zucker Diabetic Fatty (ZDF) rats… 
Highly Cited
1995
Highly Cited
1995
ISP-1/myriocin is a new type of remarkably potent immunosuppressant, the structure of which is homologous to sphingosine. ISP-1…