serine palmitoyltransferase

Known as: Palmitoyltransferase, Serine, Palmitoyl-Coenzyme A-L-Serine C-Palmitoyltransferase (Decarboxylating), Serine C Palmitoyltransferase 
A key enzyme in SPHINGOLIPIDS biosynthesis, this enzyme catalyzes the pyridoxal-5'-phosphate-dependent condensation of L-SERINE and PALMITOYL… (More)
National Institutes of Health

Topic mentions per year

Topic mentions per year

1982-2018
0102019822018

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2009
2009
Serine palmitoyltransferase (SPT) catalyzes the first committed step in sphingolipid biosynthesis. In yeast, SPT is composed of a… (More)
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2009
2009
The enzyme serine palmitoyltransferase (SPT) catalyzes the rate-limiting step in the de novo synthesis of sphingolipids… (More)
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2007
2007
Sphingolipid biosynthesis commences with the condensation of L-serine and palmitoyl-CoA to produce 3-ketodihydrosphingosine (KDS… (More)
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Highly Cited
2001
Highly Cited
2001
Hereditary sensory neuropathy type I (HSN1) is the most common hereditary disorder of peripheral sensory neurons. HSN1 is an… (More)
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Highly Cited
2000
Highly Cited
2000
The de novo pathway of sphingolipid synthesis has been identified recently as a novel means of generating ceramide during… (More)
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Highly Cited
1998
Highly Cited
1998
We reported that the lipoapoptosis of beta-cells observed in fat-laden islets of obese fa/fa Zucker Diabetic Fatty (ZDF) rats… (More)
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Highly Cited
1995
Highly Cited
1995
ISP-1/myriocin is a new type of remarkably potent immunosuppressant, the structure of which is homologous to sphingosine. ISP-1… (More)
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Highly Cited
1992
Highly Cited
1992
Serine palmitoyltransferase, 3-dehydrosphinganine reductase and sphinganine N-acyltransferase are responsible for the first steps… (More)
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1984
1984
Serine palmitoyltransferase [palmitoyl-CoA:L-serine C-palmitoyltransferase (decarboxylating) EC 2.3.1.50] catalyzes the initial… (More)
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1983
1983
Serine palmitoyltransferase (palmitoyl-CoA: L-serine C-palmitoyltransferase (decarboxylating) EC 2.3.1.50) catalyzes the first… (More)
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