Skip to search formSkip to main content
You are currently offline. Some features of the site may not work correctly.

serine palmitoyltransferase

Known as: Palmitoyltransferase, Serine, Palmitoyl-Coenzyme A-L-Serine C-Palmitoyltransferase (Decarboxylating), Serine C Palmitoyltransferase 
A key enzyme in SPHINGOLIPIDS biosynthesis, this enzyme catalyzes the pyridoxal-5'-phosphate-dependent condensation of L-SERINE and PALMITOYL… Expand
National Institutes of Health

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2011
Highly Cited
2011
The contribution of mutations in amyloid precursor protein (APP) and presenilin (PSEN) to familial Alzheimer's disease (AD) is… Expand
  • table 1
  • figure 1
  • figure 2
  • figure 3
  • figure 4
Is this relevant?
Highly Cited
2010
Highly Cited
2010
Hereditary sensory and autonomic neuropathy type I (HSAN-I) is an axonal peripheral neuropathy associated with progressive distal… Expand
  • table 1
  • table 2
  • figure 1
  • figure 2
  • figure 4
Is this relevant?
Highly Cited
2009
Highly Cited
2009
Serine palmitoyltransferase (SPT) catalyzes the first committed step in sphingolipid biosynthesis. In yeast, SPT is composed of a… Expand
Is this relevant?
Highly Cited
2005
Highly Cited
2005
The potent sphingolipid metabolite sphingosine 1-phosphate is produced by phosphorylation of sphingosine catalyzed by sphingosine… Expand
Is this relevant?
Highly Cited
2005
Highly Cited
2005
Stearoyl-CoA desaturase (SCD) has recently been shown to be a critical control point of lipid partitioning and body weight… Expand
  • figure 1
  • figure 2
  • table 1
  • figure 3
  • figure 4
Is this relevant?
Highly Cited
2001
Highly Cited
2001
Hereditary sensory neuropathy type I (HSN1) is the most common hereditary disorder of peripheral sensory neurons. HSN1 is an… Expand
  • table 1
  • table 2
  • figure 1
  • figure 2
Is this relevant?
Highly Cited
2000
Highly Cited
2000
The de novo pathway of sphingolipid synthesis has been identified recently as a novel means of generating ceramide during… Expand
Is this relevant?
Highly Cited
1998
Highly Cited
1998
We reported that the lipoapoptosis of beta-cells observed in fat-laden islets of obese fa/fa Zucker Diabetic Fatty (ZDF) rats… Expand
Is this relevant?
Highly Cited
1995
Highly Cited
1995
ISP-1/myriocin is a new type of remarkably potent immunosuppressant, the structure of which is homologous to sphingosine. ISP-1… Expand
Is this relevant?
Highly Cited
1992
Highly Cited
1992
Serine palmitoyltransferase, 3-dehydrosphinganine reductase and sphinganine N-acyltransferase are responsible for the first steps… Expand
Is this relevant?