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SPTLC1 gene

Known as: Serine Palmitoyltransferase, Long Chain Base Subunit 1 Gene, SPTLC1, LCB1 
This gene plays a role in lipid modification.
National Institutes of Health

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2013
2013
OBJECTIVES This study sought to evaluate whether supra-aortic angiography during preparatory balloon aortic valvuloplasty (BAV… Expand
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Highly Cited
2010
Highly Cited
2010
HSAN1 is an inherited neuropathy found to be associated with several missense mutations in the SPTLC1 subunit of serine… Expand
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Highly Cited
2010
Highly Cited
2010
BackgroundSphingoid bases are formed from the precursors L-serine and palmitoyl-CoA-a reaction which is catalyzed by the serine… Expand
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Highly Cited
2009
Highly Cited
2009
Hereditary sensory and autonomic neuropathies (HSAN) are clinically and genetically heterogeneous disorders characterized by… Expand
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Highly Cited
2006
Highly Cited
2006
Serine palmitoyltransferase (SPT) catalyzes the first step of sphingolipid biosynthesis. In yeast and mammalian cells, SPT is a… Expand
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Highly Cited
2001
Highly Cited
2001
Hereditary sensory neuropathy type 1 (HSN1, MIM 162400; ref. 1) genetically maps to human chromosome 9q22 (refs. 2–4). We report… Expand
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Highly Cited
2001
Highly Cited
2001
Hereditary sensory neuropathy type I (HSN1) is the most common hereditary disorder of peripheral sensory neurons. HSN1 is an… Expand
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Highly Cited
2000
Highly Cited
2000
Imbalance between cardiac oxygen supply and demand may trigger cardiac events in already vulnerable hemodialysis (HD) patients… Expand
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Review
1978
Review
1978
The vulnerability of subendocardial muscle to ischemic damage is due primarily to the greater risk of underperfusion. Recent… Expand
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1974
1974
Severe valvar aortic stenosis (VAS) and supravalvar aortic stenosis (SVAS) each may cause left ventricular (LV) subendocardial… Expand
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