Selectins

Known as: Selectin, Selectins [Chemical/Ingredient] 
Transmembrane proteins consisting of a lectin-like domain, an epidermal growth factor-like domain, and a variable number of domains that are… (More)
National Institutes of Health

Related topics

Related topics

21 relations
Binding ProteinsCell AdhesionCell Adhesion MoleculesIn Blood
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Broader (1)

Calmodulin

Narrower (7)

E-SelectinL-SelectinLECAMP-Selectin
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Papers overview

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Review
2003
Review
2003
The role of selectins in inflammation and disease.
Selectins are carbohydrate-binding molecules that bind to fucosylated and sialylated glycoprotein ligands, and are found on… (More)
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Highly Cited
2003
Highly Cited
2003
Accumulation of Tissue Factor into Developing Thrombi In Vivo Is Dependent upon Microparticle P-Selectin Glycoprotein Ligand 1 and Platelet P-Selectin
Using a laser-induced endothelial injury model, we examined thrombus formation in the microcirculation of wild-type and… (More)
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Review
2002
Review
2002
Inflammation and cancer
Recent data have expanded the concept that inflammation is a critical component of tumour progression. Many cancers arise from… (More)
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Highly Cited
2001
Highly Cited
2001
Heparin and cancer revisited: mechanistic connections involving platelets, P-selectin, carcinoma mucins, and tumor metastasis.
Independent studies indicate that expression of sialylated fucosylated mucins by human carcinomas portends a poor prognosis… (More)
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Highly Cited
1997
Highly Cited
1997
Circulating adhesion molecules VCAM-1, ICAM-1, and E-selectin in carotid atherosclerosis and incident coronary heart disease cases: the Atherosclerosis Risk In Communities (ARIC) study.
BACKGROUND Recruitment of circulating leukocytes at sites of atherosclerosis is mediated through a family of adhesion molecules… (More)
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Review
1997
Review
1997
Role of PSGL-1 binding to selectins in leukocyte recruitment.
A multistep series of adhesive and signaling events regulates inflammatory responses to infection or injury (1–3). To initiate… (More)
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Review
1995
Review
1995
The selectins: vascular adhesion molecules.
The selectin family of adhesion molecules mediates the initial attachment of leukocytes to venular endothelial cells before their… (More)
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Highly Cited
1995
Highly Cited
1995
P-selectin glycoprotein ligand-1 mediates rolling of human neutrophils on P-selectin
Neutrophils roll on P-selectin expressed by activated platelets or endothelial cells under the shear stresses in the… (More)
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Highly Cited
1993
Highly Cited
1993
Leukocyte rolling and extravasation are severely compromised in P selectin-deficient mice
P selectin, expressed on surfaces of activated endothelial cells and platelets, is an adhesion receptor for leukocytes. We report… (More)
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Highly Cited
1991
Highly Cited
1991
Leukocytes roll on a selectin at physiologic flow rates: Distinction from and prerequisite for adhesion through integrins
Rolling of leukocytes on vascular endothelial cells, an early event in inflammation, can be reproduced in vitro on artificial… (More)
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