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Selectins

Known as: Selectin, Selectins [Chemical/Ingredient] 
Transmembrane proteins consisting of a lectin-like domain, an epidermal growth factor-like domain, and a variable number of domains that are… Expand
National Institutes of Health

Related topics

Related topics

22 relations
Binding ProteinsCell AdhesionCell Adhesion MoleculesIn Blood
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Broader (1)

Calmodulin

Narrower (8)

E-SelectinL-SelectinLECAMP-Selectin
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Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Review
2018
Review
2018
The Role of Heparan Sulfate in Inflammation, and the Development of Biomimetics as Anti-Inflammatory Strategies
Key events that occur during inflammation include the recruitment, adhesion, and transmigration of leukocytes from the… Expand
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Review
2003
Review
2003
The role of selectins in inflammation and disease.
  • K. Ley
  • Trends in molecular medicine
  • 2003
    • Corpus ID: 1006507
Selectins are carbohydrate-binding molecules that bind to fucosylated and sialylated glycoprotein ligands, and are found on… Expand
Is this relevant?
Highly Cited
2003
Highly Cited
2003
Accumulation of Tissue Factor into Developing Thrombi In Vivo Is Dependent upon Microparticle P-Selectin Glycoprotein Ligand 1 and Platelet P-Selectin
Using a laser-induced endothelial injury model, we examined thrombus formation in the microcirculation of wild-type and… Expand
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Review
2002
Review
2002
Inflammation and cancer
Recent data have expanded the concept that inflammation is a critical component of tumour progression. Many cancers arise from… Expand
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Review
1998
Review
1998
Signal transduction and signal modulation by cell adhesion receptors: the role of integrins, cadherins, immunoglobulin-cell adhesion molecules, and selectins.
Cell adhesion is critical for the genesis and maintenance of both three-dimensional structure and normal function in tissues. The… Expand
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Review
1997
Review
1997
Role of PSGL-1 binding to selectins in leukocyte recruitment.
A multistep series of adhesive and signaling events regulates inflammatory responses to infection or injury (1–3). To initiate… Expand
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Review
1996
Review
1996
Selectins and their ligands: current concepts and controversies.
 
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Highly Cited
1995
Highly Cited
1995
P-selectin glycoprotein ligand-1 mediates rolling of human neutrophils on P-selectin
Neutrophils roll on P-selectin expressed by activated platelets or endothelial cells under the shear stresses in the… Expand
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Highly Cited
1993
Highly Cited
1993
Leukocyte rolling and extravasation are severely compromised in P selectin-deficient mice
P selectin, expressed on surfaces of activated endothelial cells and platelets, is an adhesion receptor for leukocytes. We report… Expand
Is this relevant?
Highly Cited
1991
Highly Cited
1991
Leukocytes roll on a selectin at physiologic flow rates: Distinction from and prerequisite for adhesion through integrins
Rolling of leukocytes on vascular endothelial cells, an early event in inflammation, can be reproduced in vitro on artificial… Expand
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