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Top 100 relevant results, sorted by most influential
Cellular and Molecular Immunology
Cellular and molecular immunology , Cellular and molecular immunology , کتابخانه الکترونیک و دیجیتال - آذرسا
Cutting Edge: Heat Shock Protein (HSP) 60 Activates the Innate Immune Response: CD14 Is an Essential Receptor for HSP60 Activation of Mononuclear Cells1
- A. Kol, A. Lichtman, R. Finberg, P. Libby, E. Kurt-Jones
- Biology, Medicine
- The Journal of Immunology
- 1 January 2000
Heat shock proteins (HSP), highly conserved across species, are generally viewed as intracellular proteins thought to serve protective functions against infection and cellular stress. Recently, we… Expand
NF-κB directs dynamic super enhancer formation in inflammation and atherogenesis.
Proinflammatory stimuli elicit rapid transcriptional responses via transduced signals to master regulatory transcription factors. To explore the role of chromatin-dependent signal transduction in the… Expand
Fulminant Myocarditis with Combination Immune Checkpoint Blockade.
- D. Johnson, Justin M. Balko, +29 authors J. Moslehi
- The New England journal of medicine
- 2 November 2016
Immune checkpoint inhibitors have improved clinical outcomes associated with numerous cancers, but high-grade, immune-related adverse events can occur, particularly with combination immunotherapy. We… Expand
Basic Immunology : Functions and Disorders of the Immune System
Chapter 1: Introduction to the Immune System The Nomenclature, General Properties, and Components of the Immune System Chapter 2: Innate Immunity The Early Defense Against Infections Chapter 3:… Expand
Chlamydial heat shock protein 60 localizes in human atheroma and regulates macrophage tumor necrosis factor-alpha and matrix metalloproteinase expression.
BACKGROUND Recent evidence has implicated Chlamydia pneumoniae in the aggravation of atherosclerosis. However, the mechanisms by which this agent affects atherogenesis remain poorly understood.… Expand
Chlamydial and human heat shock protein 60s activate human vascular endothelium, smooth muscle cells, and macrophages.
- A. Kol, T. Bourcier, A. Lichtman, P. Libby
- Medicine, Biology
- The Journal of clinical investigation
- 15 February 1999
Both chlamydial and human heat shock protein 60s (HSP 60), which colocalize in human atheroma, may contribute to inflammation during atherogenesis. We tested the hypothesis that chlamydial or human… Expand
Clonal deletion of thymocytes by circulating dendritic cells homing to the thymus
- R. Bonasio, M. L. Scimone, P. Schaerli, Nir Grabie, A. Lichtman, U. V. Andrian
- Biology, Medicine
- Nature Immunology
- 3 September 2006
Dendritic cell (DC) presentation of self antigen to thymocytes is essential to the establishment of central tolerance. We show here that circulating DCs were recruited to the thymic medulla through a… Expand