Secosteroids

Known as: Secosteroids [Chemical/Ingredient], secosteroid 
Steroids in which fission of one or more ring structures and concomitant addition of a hydrogen atom at each terminal group has occurred.
National Institutes of Health

Papers overview

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2015
2015
To investigate whether novel pathways of vitamin D3 (D3) and 7-dehydrocholesterol (7DHC) metabolism initiated by CYP11A1 and… (More)
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Review
2015
Review
2015
CYP11A1 hydroxylates the side chain of vitamin D3 (D3) in a sequential fashion [D3→20S(OH)D3→20,23(OH)2D3→17,20,23(OH)3D3], in an… (More)
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2012
2012
We describe the development of a method for the extraction and analysis of 62 sterols, oxysterols, and secosteroids from human… (More)
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2012
Review
2012
Skin, the body's largest organ, is strategically located at the interface with the external environment where it detects… (More)
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Highly Cited
2009
Highly Cited
2009
Elevated placental proinflammatory cytokine release is associated with miscarriage, preterm labor and preeclampsia. Specifically… (More)
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Review
2008
Review
2008
1,25-Dihydroxyvitamin D3 [1,25(OH)2D3], the biologically active form of vitamin D3, is a secosteroid hormone essential for bone… (More)
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Review
2007
Review
2007
Vitamin D is a secosteroid with an endocrine mechanism of action which is sequentially synthesized in humans in the skin, liver… (More)
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Highly Cited
2003
Highly Cited
2003
The conversion of vitamin D into an active ligand for the vitamin D receptor requires 25-hydroxylation in the liver and 1alpha… (More)
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Highly Cited
2002
Highly Cited
2002
In addition to its calciotropic function, the secosteroid 1,25-dihydroxyvitamin D(3) (1,25(OH)(2)D(3)) has potent nonclassical… (More)
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Review
2002
Review
2002
The active form of vitamin D, 1,25-dihydroxyvitamin D(3)[1,25(OH)(2)D(3)], is a secosteroid hormone that regulates calcium and… (More)
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