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Dehydroepiandrosterone (DHEA), DHEA sulfate, and aging: contribution of the DHEAge Study to a sociobiomedical issue.
A number of biological indices confirmed the lack of harmful consequences of this 50 mg/day DHEA administration over one year, indicating that this kind of replacement therapy normalized some effects of aging, but does not create "supermen/women" (doping).
Inter-method variability in PTH measurement: implication for the care of CKD patients.
Important inter-method variability in PTH results is found owing to both antibody specificity and standardization reasons, and it is proposed to use assay-specific decision limits for CKD patients, or to apply a correcting factor to the P TH results obtained with a given assay.
Third- or second-generation parathyroid hormone assays: a remaining debate in the diagnosis of primary hyperparathyroidism.
Third-generation PTH assays do not therefore improve the diagnosis of elevated serum PTH levels in PHPT, although there are numerical differences among the values.
Pituitary stalk interruption syndrome: a clinical-biological-genetic assessment of its pathogenesis.
Most of the patients with GHD associated with multiple anterior pituitary abnormalities and PSIS have features suggesting an antenatal origin, and the GH-N, GHRH receptor, and Pit-1 genes do not seem to be implicated in PSIS.
Vitamin D status and outcomes after renal transplantation.
Low 25-hydroxyvitamin D concentration measured 3 months after transplantation is an independent risk factor for interstitial fibrosis progression and is associated with a lower GFR 1 year after transplanting.
Vitamin D status and redefining serum parathyroid hormone reference range in the elderly.
The results strongly suggest that vitamin D status should be taken into account when establishing reference values for serum PTH in elderly subjects.
Vitamin D and clinical disease progression in HIV infection: results from the EuroSIDA study
25(OH)D deficiency was frequent in HIV-infected persons (83% on combined antiretroviral therapy), and was independently associated with a higher risk of mortality and AIDS events.