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SYTL1 gene
Known as:
JFC1
, C2 DOMAIN-CONTAINING PROTEIN JFC1
, SYNAPTOTAGMIN-LIKE 1
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National Institutes of Health
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Related topics
1 relation
Broader (1)
Genes
Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
2019
2019
The trafficking protein JFC1 regulates Rac1‐GTP localization at the uropod controlling neutrophil chemotaxis and in vivo migration
Mahalakshmi Ramadass
,
J. Johnson
,
+6 authors
S. Catz
Journal of leukocyte biology
2019
Corpus ID: 73444803
Neutrophil chemotaxis is essential in responses to infection and underlies inflammation. In neutrophils, the small GTPase Rac1…
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Highly Cited
2012
Highly Cited
2012
Deregulation of Rab and Rab Effector Genes in Bladder Cancer
Joel R. Ho
,
Elodie Chapeaublanc
,
+7 authors
B. Goud
PloS one
2012
Corpus ID: 18408782
Growing evidence indicates that Rab GTPases, key regulators of intracellular transport in eukaryotic cells, play an important…
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2011
2011
Genome-Wide DNA Methylation Analysis Reveals Phytoestrogen Modification of Promoter Methylation Patterns during Embryonic Stem Cell Differentiation
N. Sato
,
N. Yamakawa
,
Moe Masuda
,
K. Sudo
,
I. Hatada
,
M. Muramatsu
PloS one
2011
Corpus ID: 9019637
Background Environmental challenges during development affect the fetal epigenome, but the period(s) vulnerable to epigenetic…
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Highly Cited
2008
Highly Cited
2008
The Rab27a Effectors JFC1/Slp1 and Munc13‐4 Regulate Exocytosis of Neutrophil Granules
A. Brzezińska
,
J. Johnson
,
+5 authors
S. Catz
Traffic
2008
Corpus ID: 37785974
Neutrophil granules contain secretory molecules that contribute to the implementation of all neutrophil functions. The molecular…
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2005
2005
The Rab27a-binding protein, JFC1, regulates androgen-dependent secretion of prostate-specific antigen and prostatic-specific acid phosphatase.
J. Johnson
,
B. A. Ellis
,
D. Noack
,
M. Seabra
,
S. Catz
The Biochemical journal
2005
Corpus ID: 13442341
Two of the major proteins secreted by the prostate epithelium secretory cells are PSA (prostate-specific antigen) and PSAP…
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2005
2005
Akt Regulates the Subcellular Localization of the Rab27a‐Binding Protein JFC1 by Phosphorylation
J. Johnson
,
S. Pacquelet
,
William Arbuthnot Sir Lane
,
B. Eam
,
S. Catz
Traffic
2005
Corpus ID: 43900206
Here, we show that the Rab27a‐binding protein JFC1/Slp1 (synaptotagmin‐like protein) is regulated by Akt‐mediated phosphorylation…
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2002
2002
The C2A domain of JFC1 binds to 3′-phosphorylated phosphoinositides and directs plasma membrane association in living cells
S. Catz
,
J. Johnson
,
B. Babior
Proceedings of the National Academy of Sciences…
2002
Corpus ID: 25597966
Phosphatidylinositol 3-kinase products play a central role in the regulation of several intracellular pathways via adaptor…
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2002
2002
JFC1 is transcriptionally activated by nuclear factor-kappaB and up-regulated by tumour necrosis factor alpha in prostate carcinoma cells.
S. Catz
,
B. Babior
,
J. Johnson
The Biochemical journal
2002
Corpus ID: 44983865
The human promoter region of JFC1, a phosphatidylinositol 3,4,5-trisphosphate binding ATPase, was isolated by amplification of a…
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2001
2001
JFC1, a Novel Tandem C2 Domain-containing Protein Associated with the Leukocyte NADPH Oxidase*
J. K. McAdara Berkowitz
,
S. Catz
,
J. Johnson
,
J. Ruedi
,
V. Thon
,
B. Babior
The Journal of Biological Chemistry
2001
Corpus ID: 26645108
We have employed a yeast two-hybrid system to screen a B lymphoblast-derived cDNA library, searching for regulatory components of…
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2001
2001
Characterization of the nucleotide-binding capacity and the ATPase activity of the PIP3-binding protein JFC1
S. Catz
,
J. Johnson
,
B. Babior
Proceedings of the National Academy of Sciences…
2001
Corpus ID: 23499748
In this work, we demonstrate that the phosphatidylinositol 3,4,5-trisphosphate-binding protein JFC1 is an ATP-binding protein…
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