SUFU gene

Known as: PRO1280, SUFUH, SUFU 
This gene plays a role in the regulation of both transcription and signaling.
National Institutes of Health

Topic mentions per year

Topic mentions per year

1990-2018
05101519902018

Papers overview

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2014
2014
PURPOSE Heterozygous germline PTCH1 mutations are causative of Gorlin syndrome (naevoid basal cell carcinoma), but detection… (More)
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2012
2012
Meningiomas are the most common primary tumors of the CNS and account for up to 30% of all CNS tumors. An increased risk of… (More)
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2012
2012
Nevoid basal cell carcinoma syndrome (NBCCS) is an autosomal dominant disorder characterized by developmental defects and… (More)
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Highly Cited
2010
Highly Cited
2010
Gli2 and Gli3 are primary transcriptional regulators that mediate hedgehog (Hh) signaling. Mechanisms that stabilize and… (More)
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2010
2010
Bacteria use three distinct systems for iron-sulfur (Fe/S) cluster biogenesis: the ISC, SUF, and NIF machineries. The ISC and SUF… (More)
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2009
2009
Gorlin syndrome (GS) is inherited in an autosomal dominant pattern with high-penetrance and is characterized by a range of… (More)
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Highly Cited
2008
Highly Cited
2008
Genetic studies in the mouse have shown that Intraflagellar Transport (IFT) is essential for mammalian Hedgehog (Hh) signal… (More)
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2004
2004
Germline mutations of APC in patients with Turcot syndrome (colon cancer and medulloblastoma), was well as somatic mutations of… (More)
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Highly Cited
2003
Highly Cited
2003
The Hedgehog signaling pathway is involved in both development and cancer induction in a wide range of organisms. The end point… (More)
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Highly Cited
2002
Highly Cited
2002
The sonic hedgehog (SHH) signaling pathway directs the embryonic development of diverse organisms and is disrupted in a variety… (More)
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