Suppressor of Fused Homolog
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Mutations in mouse intraflagellar transport–A complex genes alter Sonic hedgehog signaling because of their effects on cilia… Expand ABSTRACT Copper and iron are essential elements for cellular growth. Although bacteria have to overcome limitations of these… Expand Gli2 and Gli3 are primary transcriptional regulators that mediate hedgehog (Hh) signaling. Mechanisms that stabilize and… Expand Gorlin syndrome (GS) is inherited in an autosomal dominant pattern with high‐penetrance and is characterized by a range of… Expand The naevoid basal cell carcinoma syndrome (NBCCS) is caused by mutations in the hedgehog receptor PTCH gene. It is characterized… Expand Background Basal cell carcinoma (BCC) of the skin is the most common human cancer. The genetic alterations underlying BCC… Expand The Hedgehog signaling pathway is involved in both development and cancer induction in a wide range of organisms. The end point… Expand The sonic hedgehog (SHH) signaling pathway directs the embryonic development of diverse organisms and is disrupted in a variety… Expand Sufu or furu is a fermented soybean product originating in China. It is a cheese-like product with a spreadable creamy… Expand Sonic hedgehog, Patched and Gli are components of a mammalian signalling pathway that has been conserved during evolution and… Expand