Suppressor of Fused Homolog

Known as: SUFU, SUFUH 
Suppressor of fused homolog (484 aa, ~54 kDa) is encoded by the human SUFU gene. This protein plays a role in both the hedgehog pathway and… (More)
National Institutes of Health

Papers overview

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Highly Cited
2012
Highly Cited
2012
Two intraflagellar transport (IFT) complexes, IFT-A and IFT-B, build and maintain primary cilia and are required for activity of… (More)
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2011
2011
Glis3 is a member of the Glis subfamily of Krüppel-like zinc finger transcription factors. Recently, Glis3 has been linked to… (More)
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Highly Cited
2010
Highly Cited
2010
Gli2 and Gli3 are primary transcriptional regulators that mediate hedgehog (Hh) signaling. Mechanisms that stabilize and… (More)
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Highly Cited
2010
Highly Cited
2010
Copper and iron are essential elements for cellular growth. Although bacteria have to overcome limitations of these metals by… (More)
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2008
2008
As a physically binding protein of GLI1 transcription factor, Suppressor-of-Fused (SUFU) has been placed in the center of… (More)
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2008
2008
Hedgehog (HH) signaling is one of the key pathways with major significance for embryogenesis, tumorigenesis, and stem cell… (More)
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2008
2008
transport; both proteins belong to the RND superfamily of proteins, originally defined by bacterial channel and transporter… (More)
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Highly Cited
2005
Highly Cited
2005
BACKGROUND Basal cell carcinoma (BCC) of the skin is the most common human cancer. The genetic alterations underlying BCC… (More)
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Highly Cited
2002
Highly Cited
2002
The sonic hedgehog (SHH) signaling pathway directs the embryonic development of diverse organisms and is disrupted in a variety… (More)
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Highly Cited
1999
Highly Cited
1999
Sonic hedgehog, Patched and Gli are components of a mammalian signalling pathway that has been conserved during evolution and… (More)
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