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Suppressor of Fused Homolog

Known as: SUFU, SUFUH 
Suppressor of fused homolog (484 aa, ~54 kDa) is encoded by the human SUFU gene. This protein plays a role in both the hedgehog pathway and… Expand
National Institutes of Health

Papers overview

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Highly Cited
2012
Highly Cited
2012
Mutations in mouse intraflagellar transport–A complex genes alter Sonic hedgehog signaling because of their effects on cilia… Expand
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Highly Cited
2010
Highly Cited
2010
ABSTRACT Copper and iron are essential elements for cellular growth. Although bacteria have to overcome limitations of these… Expand
Highly Cited
2010
Highly Cited
2010
Gli2 and Gli3 are primary transcriptional regulators that mediate hedgehog (Hh) signaling. Mechanisms that stabilize and… Expand
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Highly Cited
2009
Highly Cited
2009
Gorlin syndrome (GS) is inherited in an autosomal dominant pattern with high‐penetrance and is characterized by a range of… Expand
Highly Cited
2006
Highly Cited
2006
The naevoid basal cell carcinoma syndrome (NBCCS) is caused by mutations in the hedgehog receptor PTCH gene. It is characterized… Expand
Highly Cited
2005
Highly Cited
2005
Background  Basal cell carcinoma (BCC) of the skin is the most common human cancer. The genetic alterations underlying BCC… Expand
Highly Cited
2003
Highly Cited
2003
The Hedgehog signaling pathway is involved in both development and cancer induction in a wide range of organisms. The end point… Expand
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Highly Cited
2002
Highly Cited
2002
The sonic hedgehog (SHH) signaling pathway directs the embryonic development of diverse organisms and is disrupted in a variety… Expand
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Review
2001
Review
2001
Sufu or furu is a fermented soybean product originating in China. It is a cheese-like product with a spreadable creamy… Expand
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Highly Cited
1999
Highly Cited
1999
Sonic hedgehog, Patched and Gli are components of a mammalian signalling pathway that has been conserved during evolution and… Expand
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