Skip to search formSkip to main contentSkip to account menu

SU 9516

Known as: 3-(1-(3H-Imidazol-4-yl)-meth-(Z)-ylidene)-5-methoxy-1,3-dihydro-indol-2-one, SU9516 
National Institutes of Health

Related topics

Related topics

2 relations

Broader (2)

ImidazolesIndoles

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2020
2020
Effect of cell-extracellular matrix interaction on myogenic characteristics and artificial skeletal muscle tissue.
2017
2017
CDK inhibitor SU9516 induces tetraploid blastocyst formation from parthenogenetically activated porcine embryos
To examine the effect of SU9516, a cyclin-dependent kinase inhibitor, on the induction of tetraploid blastocyst formation in… 
2017
2017
Commentary: SU9516 increases α7β1 Integrin and Ameliorates Disease Progression in the mdx Mouse Model of Duchenne Muscular Dystrophy
Duchenne muscular dystrophy (DMD) is a debilitating X-linked neuromuscular disease with an incidence of 1 in every 5000 boys1. It… 
2014
2014
Glucocorticoid sensitisation in Mixed Lineage Leukaemia-rearranged acute lymphoblastic leukaemia by the pan-BCL-2 family inhibitors gossypol and AT-101.
2010
2010
Cyclin-Dependent Kinase Inhibitors Enhance Sensitivity to Methotrexate In Human T-Cell Leukemia Jurkat Cells
Abstract 3976 Methotrexate (MTX), a classical anti-folate drug, has been used in the treatment of various hematological… 
2008
2008
CDK inhibitor enhances the sensitivity to 5-fluorouracil in colorectal cancer cells.
Thymidylate synthase (TS) is a dNTP synthetic enzyme and is also a target enzyme of 5-fluorouracil (5-FU). 5-FU is one of the… 
Highly Cited
2006
Highly Cited
2006
The Three-Substituted Indolinone Cyclin-Dependent Kinase 2 Inhibitor 3-[1-(3H-Imidazol-4-yl)-meth-(Z)-ylidene]-5-methoxy-1,3-dihydro-indol-2-one (SU9516) Kills Human Leukemia Cells via Down…
Mechanisms of lethality of the three-substituted indolinone and putatively selective cyclin-dependent kinase (CDK)2 inhibitor 3… 
2005
2005
Inhibiting CDK2: A Study with First Principles and Classical Methods
Submitted for the MAR05 Meeting of The American Physical Society Inhibiting CDK2: A Study with First Principles and Classical… 
2003
2003
Novel pyrrolyllactone and pyrrolyllactam indolinones as potent cyclin-dependent kinase 2 inhibitors.
2002
2002
SU9516, a cyclin-dependent kinase 2 inhibitor, promotes accumulation of high molecular weight E2F complexes in human colon carcinoma cells.
By clicking accept or continuing to use the site, you agree to the terms outlined in our Privacy Policy (opens in a new tab), Terms of Service (opens in a new tab), and Dataset License (opens in a new tab)