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SU 11248

Known as: SU 011248, SU011248, SU11248 
 
National Institutes of Health

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Highly Cited
2009
Highly Cited
2009
Herein we report that the VEGFR/PDGFR kinase inhibitor sunitinib/SU11248 can accelerate metastatic tumor growth and decrease… Expand
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Review
2007
Review
2007
  • L. Chow, S. Eckhardt
  • Journal of clinical oncology : official journal…
  • 2007
  • Corpus ID: 20450892
Sunitinib (SU011248) is an oral small molecular tyrosine kinase inhibitor that exhibits potent antiangiogenic and antitumor… Expand
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Highly Cited
2006
Highly Cited
2006
PURPOSE Renal cell carcinoma (RCC) is characterized by loss of von Hippel Lindau tumor suppressor gene activity, resulting in… Expand
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Highly Cited
2006
Highly Cited
2006
PURPOSE To establish the safety, pharmacokinetics, and recommended dose of sunitinib, a novel oral multitargeting tyrosine kinase… Expand
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Highly Cited
2005
Highly Cited
2005
PURPOSE A transgenic mouse model has revealed parameters of the angiogenic switch during multistep tumorigenesis of pancreatic… Expand
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Highly Cited
2005
Highly Cited
2005
Fifteen patients with refractory AML were treated in a phase 1 study with SU11248, an oral kinase inhibitor of fms-like tyrosine… Expand
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Highly Cited
2004
Highly Cited
2004
The aim of the study was to investigate inhibitory effects of the receptor tyrosine kinase (RTK) inhibitor SU11248 against CSF-1R… Expand
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Highly Cited
2003
Highly Cited
2003
One challenging aspect in the clinical development of molecularly targeted therapies, which represent a new and promising… Expand
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Highly Cited
2003
Highly Cited
2003
FLT3 (fms-related tyrosine kinase/Flk2/Stk-2) is a receptor tyrosine kinase (RTK) primarily expressed on hematopoietic cells. In… Expand
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Highly Cited
2003
Highly Cited
2003
The purpose of this study was to evaluate the activity of the indolinone kinase inhibitor SU11248 against the receptor tyrosine… Expand
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