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STI571

Known as: STI 571, STI-571 
National Institutes of Health

Related topics

Related topics

3 relations
Gleevec

Broader (2)

Imatinib mesylateimatinib

Papers overview

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Highly Cited
2005
Highly Cited
2005
Modulation of bone microenvironment with zoledronate enhances the therapeutic effects of STI571 and paclitaxel against experimental bone metastasis of human prostate cancer.
Prostate cancer cells metastasize to the bone where their interaction with osteoclasts and osteoblasts can lead to alterations in… 
2005
2005
Patupilone (epothilone B, EPO906) and imatinib (STI571, Glivec) in combination display enhanced antitumour activity in vivo against experimental rat C6 glioma
PurposeThe microtubule-stabilizing agent patupilone (epothilone B, EPO906) and the tyrosine kinase inhibitor imatinib (STI571… 
2004
2004
Liquid chromatographic method for detection and quantitation of STI-571 and its main metabolite N-desmethyl-STI in plasma, urine, cerebrospinal fluid, culture medium and cell preparations.
Review
2004
Review
2004
Mechanisms of Resistance to STI571 (Imatinib) in Philadelphia-chromosome Positive Acute Lymphoblastic Leukemia
Resistance against STI571 (Imatinib) appears to be multifactorial, but the most likely mechanisms can be broadly categorized as… 
2004
2004
Different roles of p38 MAPK and ERK in STI571‐induced multi‐lineage differentiation of K562 cells
STI571 is a specific tyrosine kinase inhibitor of Abl kinase. It was previously reported that STI571 induced hemoglobin synthesis… 
Highly Cited
2003
Highly Cited
2003
The reappraisal of gastrointestinal stromal tumors: from Stout to the KIT revolution
For five decades gastrointestinal stromal tumors (GISTs) truly have represented one of the most confusing as well as neglected… 
Highly Cited
2003
Highly Cited
2003
Imatinib mesylate (STI571) inhibits multiple myeloma cell proliferation and potentiates the effect of common antimyeloma agents
Summary.  c‐Kit has been shown to be mutated in several types of tumours, and its activity has been correlated with increased… 
2003
2003
Quantification of the anticancer agent STI-571 in erythrocytes and plasma by measurement of sediment technology and liquid chromatography-tandem mass spectrometry.
2003
2003
Marked regression of metastatic pilocytic astrocytoma during treatment with imatinib mesylate (STI-571, Gleevec): a case report and laboratory investigation.
Pilocytic astrocytomas are the most common childhood glioma. Most children with pilocytic astrocytomas survive many years with… 
1999
1999
A model for elastic-plastic pressure sensitive materials subjected to large deformations
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