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STEAP1 gene

Known as: SIX-TRANSMEMBRANE EPITHELIAL ANTIGEN OF PROSTATE, Six Transmembrane Epithelial Antigen of the Prostate 1 Gene, STEAP1 
This gene plays a role at cell-cell junctions.
National Institutes of Health

Related topics

Related topics

2 relations
Metalloreductase STEAP1Oxidation-Reduction

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2018
2018
Abstract LB-106: Allorepertoire-derived HLA class I/peptide-specific T cell receptor transgenic CD4+T cells mediate antitumor responses in Ewing sarcoma mimicking allo-rejection
Introduction: Innovative therapies are urgently warranted to cure patients with advanced Ewing sarcoma (ES). Specific cellular… 
2016
2016
Isolation and purification of STEAP1 protein fragment in Escherichia coli cells: a potential target for prostate cancer
2016
2016
Biosynthesis and isolation of STEAP1 protein from Escherichia coli cells lysates
2015
2015
STEAP1 as a predictive biomarker for antibody-drug conjugate (ADC) activity in metastatic castration resistant prostate cancer (mCRPC).
5029 Background: STEAP1 is overexpressed in mCRPC and is an ADC target. STEAP1 expression in tissue assayed by IHC, protein and… 
2015
2015
Abstract 5258: Expression analysis of STEAP1 in breast cancer patients as therapeutic target
Proceedings: AACR 106th Annual Meeting 2015; April 18-22, 2015; Philadelphia, PA Objective: The six transmembrane epithelial… 
2014
2014
Abstract 2069: Initial PET imaging and pharmacokinetic results from a Phase I/II study of Zr-89-labeled anti-STEAP1 antibody in metastatic castrate-resistant prostate cancer (mCRPC) patients
Proceedings: AACR Annual Meeting 2014; April 5-9, 2014; San Diego, CA Introduction: STEAP1 (Six Transmembrane Epithelial Antigen… 
2013
2013
A phase I study of the safety and pharmacokinetics of DSTP3086S, an anti-STEAP1 antibody-drug conjugate (ADC), in patients (pts) with metastatic castration-resistant prostate cancer (CRPC).
5020 Background: Six-transmembrane epithelial antigen of the prostate-1 (STEAP1) protein is a cell-surface antigen overexpressed… 
2011
2011
Cancer Genes and Genomics STEAP 1 Is Associated with the Invasive and Oxidative Stress Phenotype of Ewing Tumors
Ewing tumors comprise the second most common type of bone-associated cancer in children and are characterized by oncogenic EWS… 
2009
2009
STEAP 4 regulates focal adhesion kinase activation and CpG motifs within STEAP 4 promoter region are frequently methylated in DU 145 , human androgen-independent prostate cancer cells
The possible roles of STEAP4 in cancer progression have not been reported. In this study, we report that STEAP4 expression is… 
2005
2005
Candidates for Prostate Cancer Immunotherapy Six-Transmembrane Epithelial Antigen of Prostate-3 as Human CTL Epitopes Prostatic Acid Phosphatase-3 and Updated
Specific immunotherapy of prostate cancer may be an alternative or be complementary to other approaches for treatment of… 
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