STAT5a Transcription Factor

&NA; Although anti‐programmed death ligand‐1 (PD‐L1) therapy has shown light in treatment of gastric cancer, only a limited… Expand

Tumor suppressors known to date impede cancer growth by arresting the cell cycle or promoting apoptosis. Here we show that… Expand

The growth hormone (GH) receptor (R)-mediated JAK2 (Janus kinase-2)-STAT5 (signaling transducer and activator of transcription-5… Expand

The signal transducer and activator of transcription (Stat) gene family comprises seven members with similarities in their domain… Expand

Prolactin (PRL) plays a central and crucial role in the regulation of milk protein gene expression in mammary epithelial cells… Expand

We previously identified a constitutively active form of STAT (signal transducer and activator of transcription) 5A by polymerase… Expand

ABSTRACT The lactogenic hormones, i.e., prolactin and glucocorticoids, act in concert to stimulate transcription factors… Expand

We have isolated a second human Stat5 cDNA, Stat5B, and demonstrated that the genes encoding both Stat5A and Stat5B are located… Expand

Granulocyte-macrophage colony-stimulating factor (GM-CSF) induces immediate effects in monocytes by activation of the Janus… Expand

The hormonal induction of the beta-casein gene in mammary epithelial cells is dependent on the action of peptide and steroid… Expand