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Breast cancer stem-like cells (BCSC) are implicated in cancer recurrence and metastasis of triple-negative breast cancer (TNBC… Expand Colorectal cancer (CRC) is one of the leading causes of cancer mortality worldwide. Aberrant sialylation is crucially involved in… Expand We have demonstrated previously the involvement of certain glycosphingolipids (GSLs) in ‘contact inhibition’ (dependent on cell… Expand An immunotherapeutic strategy is discussed supporting anti-tumor activity toward malignancies overexpressing ganglioside D3. GD3… Expand Repeated cold stress (RCS) is known to transiently induce functional disorders associated with hypotension and hyperalgesia. In… Expand Recent data have underlined a possible role of GD3 synthase (GD3S) and complex gangliosides in Estrogen Receptor (ER) negative… Expand Many studies have been devoted to the identification of genes involved in experience-dependent plasticity in the visual cortex… Expand Gangliosides have been shown to be necessary for beta-amyloid (Abeta) binding and aggregation. GD3 synthase (GD3S) is responsible… Expand Multiple sclerosis (MS) is an inflammatory demyelinating disease of the central nervous system of unknown etiology with both… Expand GD3 synthase (CMP-NeuAc:NeuAc alpha 2-3Gal beta 1-4Glc beta 1-1'Cer alpha 2,8-sialyltransferase) is a member of the… Expand