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ST8SIA1 gene

Known as: GANGLIOSIDE GD3 SYNTHASE, SIALYLTRANSFERASE 8, SIAT8 
National Institutes of Health

Related topics

Related topics

3 relations
ST8SIA3 geneST8SIA4 genealpha-N-acetylneuraminate alpha-2,8-sialyltransferase

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2019
2019
Abstract 1169: Characterization of a small molecule inhibitor for GD3 synthase (ST8SIA1), a novel target in breast cancer stem-like cells
We reported that GD2 selectively identifies breast cancer stem-like cells (BCSCs) in TNBCs and that the enzyme ST8SIA1 regulates… 
2018
2018
Abstract 1929: ST8SIA1 is a novel therapeutic target in TNBC: Regulates FAK-PI3K-AKT-mTOR signaling to promote tumor growth and metastasis
We identified ganglioside GD2 as a breast cancer stem cell (BCSC) marker and that GD3 synthase (ST8SIA1) regulates GD2 expression… 
2017
2017
Identification and Functional Characterization of ST3GAL5 and ST8SIA1 Variants in Patients with Thyroid-Associated Ophthalmopathy
Purpose This study was conducted to identify and to functionally characterize genetic variants in ST3GAL5 and ST8SIA1 in Korean… 
2017
2017
Abstract 2898: ST8SIA1 is up-regulated in triple negative breast cancer and its expression is positively correlated withTP53mutations and a cancer stem cell gene signature
We discovered ganglioside GD2 as a breast cancer stem cell (BCSCs) marker in triple negative breast cancer (TNBC). GD2… 
2017
2017
Identification and Functional Characterization of ST 3 GAL 5 and ST 8 SIA 1 Variants in Patients with Thyroid-Associated Ophthalmopathy
Thyroid-associated ophthalmopathy (TAO) is an ophthalmic disease that frequently accompanies Graves’ disease (GD). In general, 25… 
2017
2017
Abstract P5-07-02: ST8SIA1 regulates tumorigenesis in triple negative breast cancer
Recurrence in breast cancer is mainly due to metastases and drug resistance in a fraction of primary tumors cells which are also… 
2017
2017
Abstract 2875: Knockout of ST8SIA1 inhibits tumorigenesis in triple negative breast cancer by inducing PTEN and ganglioside GM1 mediated tumor growth arrest
We found that ganglioside GD2 is a biomarker for breast cancer stem cell (BCSCs) in triple negative breast cancer (TNBC) and that… 
2015
2015
Peripheral gene expression profile of mechanical hyperalgesia induced by repeated cold stress in SHRSP5/Dmcr rats
Repeated cold stress (RCS) is known to transiently induce functional disorders associated with hypotension and hyperalgesia. In… 
1996
1996
Chromosome mapping of the GD3 synthase gene (SIAT8) in human and mouse.
GD3 synthase (CMP-NeuAc:NeuAc alpha 2-3Gal beta 1-4Glc beta 1-1'Cer alpha 2,8-sialyltransferase) is a member of the… 
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