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ST2825

 
National Institutes of Health

Topic mentions per year

Topic mentions per year

2007-2017
02420072017

Related topics

Related topics

1 relation

Broader (1)

Spiro Compounds

Related mentions per year

Related mentions per year

1964-2018
1960198020002020
ST2825
Spiro Compounds

Papers overview

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2017
2017
MYD88 Inhibitor ST2825 Suppresses the Growth of Lymphoma and Leukaemia Cells.
BACKGROUND/AIM Myeloid differentiation primary response gene 88 (MYD88), which activates the nuclear factor kappa B (NF-κB… (More)
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2017
2017
Inhibition of myeloid differentiation primary response protein 88 provides neuroprotection in early brain injury following experimental subarachnoid hemorrhage
Accumulating of evidence suggests that activation of nuclear factor-kappa B (NF-κB) and mitogen-activated protein kinases (MAPKs… (More)
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2016
2016
Inhibition of myeloid differentiation factor 88(MyD88) by ST2825 provides neuroprotection after experimental traumatic brain injury in mice.
Myeloid differentiation factor 88(MyD88) is an endogenous adaptor protein that plays an important role in coordinating… (More)
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2016
2016
Effect of ST2825 on the proliferation and apoptosis of human hepatocellular carcinoma cells.
The purpose of this study was to investigate the effect of ST2825, an inhibitor of myeloid differentiation factor 88 (MyD88), on… (More)
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2016
2016
Dioscin reduces lipopolysaccharide-induced inflammatory liver injury via regulating TLR4/MyD88 signal pathway.
We previously reported the effects of dioscin against carbon tetrachloride-, acetaminophen- and alcohol-induced acute liver… (More)
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2016
2016
Short-term MyD88 inhibition ameliorates cardiac graft rejection and promotes donor-specific hyporesponsiveness of skin grafts in mice.
Recognition of evolutionarily conserved ligands by Toll-like receptors (TLRs) triggers signaling cascades in innate immune cells… (More)
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2016
2016
Dioscin alleviates lipopolysaccharide-induced inflammatory kidney injury via the microRNA let-7i/TLR4/MyD88 signaling pathway.
We previously reported the potent effect of dioscin against renal ischemia/reperfusion injury, but little is known about the role… (More)
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2016
2016
Polysaccharopeptide exerts immunoregulatory effects via MyD88-dependent signaling pathway.
AIMS The present study is to investigate the immunomodulatory mechanism and related pathways of polysaccharopeptide (PSP) in mice… (More)
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2015
2015
Dioscin attenuates renal ischemia/reperfusion injury by inhibiting the TLR4/MyD88 signaling pathway via up-regulation of HSP70.
We previously reported the effect of dioscin against hepatic ischemia/reperfusion injury (IRI) in rats. However, little is known… (More)
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2007
2007
Pivotal Advance: Inhibition of MyD88 dimerization and recruitment of IRAK1 and IRAK4 by a novel peptidomimetic compound.
MyD88 is an adaptor protein, which plays an essential role in the intracellular signaling elicited by IL-1R and several TLRs… (More)
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