Inhibition of myeloid differentiation primary response protein 88 provides neuroprotection in early brain injury following experimental subarachnoid hemorrhage

@inproceedings{Yan2017InhibitionOM,
  title={Inhibition of myeloid differentiation primary response protein 88 provides neuroprotection in early brain injury following experimental subarachnoid hemorrhage},
  author={Huiying Yan and Dingding Zhang and Yongxiang Wei and Hongbin Ni and Weibang Liang and Huasheng Zhang and Shuangying Hao and Wei Jin and Kuanyu Li and Chunhua Hang},
  booktitle={Scientific Reports},
  year={2017}
}
Accumulating of evidence suggests that activation of nuclear factor-kappa B (NF-κB) and mitogen-activated protein kinases (MAPKs) exacerbates early brain injury (EBI) following subarachnoid hemorrhage (SAH) by provoking pro-inflammatory and pro-apoptotic signaling. Myeloid differentiation primary response protein 88 (MyD88) is an endogenous adaptor protein… CONTINUE READING