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ST-246

Known as: ST 246 
National Institutes of Health

Related topics

Related topics

3 relations

Broader (2)

BenzamidesIsoindoles

Narrower (1)

Tecovirimat

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2013
2013
Pharmacokinetics and Interspecies Allometric Scaling of ST-246, an Oral Antiviral Therapeutic for Treatment of Orthopoxvirus Infection
Plasma pharmacokinetics of ST-246, smallpox therapeutic, was evaluated in mice, rabbits, monkeys and dogs following repeat oral… 
2013
2013
Plots of mean plasma concentration versus time profiles in beagle dogs, following repeat oral administrations of ST-246 by gavage at a dose of 30 mg/kg seven consecutive days.
Review
2013
Review
2013
Research on substances with activity against orthopoxviruses.
Although smallpox was eradicated over 30 years ago, the disease remains a major threat. High mortality, high infectivity and low… 
2012
2012
Pharmacokinetic Comparison of a Single Oral Dose of Polymorph Form I versus Form V Capsules of the Antiorthopoxvirus Compound ST-246 in Human Volunteers
ABSTRACT ST-246, a novel compound that inhibits egress of orthopoxvirus from mammalian cells, is being tested as a treatment for… 
2011
2011
St-246 liquid formulations and methods
The present invention provides a novel process for making a novel liquid formulation and the formulation for solubilizing a… 
2011
2011
Polymorph forms and methods of preparation st-246
Discloses 4-trifluoromethyl -N- (3,3a, 4,4a, 5,5a, 6,6a- octahydro-1,3-dioxo-4,6-ethenylene cyclopropa [ f] isoindol -2 (1H) - yl… 
2008
2008
Highlights on the mode of action of ST-246, an anti-orthopoxviral compound
2007
2007
Specific inhibition of Orthopoxvirus replication by small interfering RNA: involvement in the mechanism of action of ST-246
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