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SSR 240612

Known as: SSR-240612, SSR240612 
National Institutes of Health

Papers overview

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Review
2016
Review
2016
Potentiation of Paclitaxel-Induced Pain Syndrome in Mice by Angiotensin I Converting Enzyme Inhibition and Involvement of Kinins
Paclitaxel is a chemotherapeutic agent used to treat solid tumours. However, it causes an acute and neuropathic pain syndrome… 
Highly Cited
2013
Highly Cited
2013
Cognitive and cerebrovascular improvements following kinin B1 receptor blockade in Alzheimer’s disease mice
BackgroundRecent evidence suggests that the inducible kinin B1 receptor (B1R) contributes to pathogenic neuroinflammation induced… 
2012
2012
Suppression of Vascular Inflammation by Kinin B1 Receptor Antagonism in a Rat Model of Insulin Resistance
Background: Kinin B1 receptor (B1R) intervenes in a positive feedback loop to amplify and perpetuate the vascular oxidative… 
2011
2011
Modulation of retinal blood flow by kinin B₁ receptor in Streptozotocin-diabetic rats.
Highly Cited
2010
Highly Cited
2010
Kinin B1 Receptor Enhances the Oxidative Stress in a Rat Model of Insulin Resistance: Outcome in Hypertension, Allodynia and Metabolic Complications
Background Kinin B1 receptor (B1R) is induced by the oxidative stress in models of diabetes mellitus. This study aims at… 
2010
2010
The role of kinin B1 and B2 receptors in the scratching behaviour induced by proteinase‐activated receptor‐2 agonists in mice
Background and purpose:  Activation of the proteinase‐activated receptor‐2 (PAR‐2) induces scratching behaviour in mice. Here, we… 
2010
2010
Kinin B1 receptors mediate depression-like behavior response in stressed mice treated with systemic E. coli lipopolysaccharide
BackgroundKinin B1 receptors are inducible molecules up-regulated after inflammatory stimuli. This study evaluated the relevance… 
Highly Cited
2008
Highly Cited
2008
Evidence for the role of neurogenic inflammation components in trypsin‐elicited scratching behaviour in mice
We investigated the mechanisms underlying the pruritogenic response induced by trypsin in mice, to assess the relevance of… 
2008
2008
The relevance of kinin B1 receptor upregulation in a mouse model of colitis
Kinins are implicated in many pathophysiological conditions, and recent evidence has suggested their involvement in colitis. This… 
Highly Cited
2008
Highly Cited
2008
Kinin B1 Receptor Deficiency Leads to Leptin Hypersensitivity and Resistance to Obesity
OBJECTIVE—Kinins mediate pathophysiological processes related to hypertension, pain, and inflammation through the activation of… 
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