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SRT1720

National Institutes of Health

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Heterocyclic Compounds, 4 or More Rings

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2016
2016
Comparative effects of Quercetin and SRT1720 against D-galactosamine/lipopolysaccharide-induced hepatotoxicity in rats: biochemical and molecular biological investigations.
OBJECTIVE Quercetin, a plant flavonoid with potent antioxidant action, has been shown to be ameliorative against different types… 
2016
2016
Inhibitory effects of SRT1720 on the apoptosis of rabbit chondrocytes by activating SIRT1 via p53/bax and NF-κB/PGC-1α pathways
SummarySRT1720, a new discovered drug, was reported to activate silent information regulator 1 (SIRT1) and inhibit the… 
2016
2016
Inhibitory effects of SRT1720 on the apoptosis of rabbit chondrocytes by activating SIRT1 via p53/bax and NF-κB/PGC-1α pathways
SRT1720, a new discovered drug, was reported to activate silent information regulator 1 (SIRT1) and inhibit the chondrocyte… 
2015
2015
Resveratrol suppresses TGF-β-induced VEGF synthesis in osteoblasts: Inhibition of the p44/p42 MAPKs and SAPK/JNK pathways.
Resveratrol, which is found in grape and berry skins and red wine, is generally known to be beneficial for human health due to… 
2015
2015
Reverse chemomodulatory effects of the SIRT1 activators resveratrol and SRT1720 in Ewing’s sarcoma cells: resveratrol suppresses and SRT1720 enhances etoposide- and vincristine-induced anticancer…
PurposeSIRT1-activating compounds (STACs) may have potential in the management of cancer. However, the best-studied STAC, the… 
2015
2015
SIRTUIN 1 ACTIVATOR SRT1720 PROTECTS AGAINST ORGAN INJURY INDUCED BY INTESTINAL ISCHEMIA-REPERFUSION
ABSTRACT Intestinal ischemia-reperfusion (I/R) occurs in various clinical situations and causes local and remote organ injury… 
2014
2014
Mass spectrometric studies on the in vivo metabolism and excretion of SIRT1 activating drugs in rat urine, dried blood spots, and plasma samples for doping control purposes.
2012
2012
Sirtuin biology and relevance to diabetes treatment.
Sirtuins are a group of NAD(+)-dependent enzymes that post-translationally modify histones and other proteins. Among seven… 
2012
2012
SRT1720, a SIRT1 Activator, Aggravates Bleomycin-Induced Lung Injury in Mice
Diagnosis and management of interstitial lung diseases (ILDs), caused by lung epithelial injury followed by apoptosis, are often… 
Highly Cited
2009
Highly Cited
2009
Knockdown of Dicer in MCF-7 human breast carcinoma cells results in G1 arrest and increased sensitivity to cisplatin.
Aberrant expression of microRNAs (miRNAs) in various human cancers suggests a role for miRNAs in tumorigenesis. Dicer is an… 
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