SRT1720

 
National Institutes of Health

Papers overview

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Highly Cited
2014
Highly Cited
2014
The prevention or delay of the onset of age-related diseases prolongs survival and improves quality of life while reducing the… (More)
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Highly Cited
2012
Highly Cited
2012
Chronic obstructive pulmonary disease/emphysema (COPD/emphysema) is characterized by chronic inflammation and… (More)
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2012
2012
Silent information regulator 2 (SIR2) is a highly conserved protein, the mammalian orthologue of which, SIRT1… (More)
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Highly Cited
2011
Highly Cited
2011
Sirt1 is an NAD(+)-dependent deacetylase that extends lifespan in lower organisms and improves metabolism and delays the onset of… (More)
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Highly Cited
2010
Highly Cited
2010
Sirtuins catalyze NAD(+)-dependent protein deacetylation and are critical regulators of transcription, apoptosis, metabolism, and… (More)
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2010
2010
Mitochondrial biogenesis occurs under basal conditions and is an adaptive response initiated by cells to maintain energetic… (More)
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2010
2010
BACKGROUND SRT1720 and SRT2183 were described recently as activators of the NAD+-dependent deacetylase, SIRT1. These molecules… (More)
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Highly Cited
2009
Highly Cited
2009
Nonalcoholic fatty liver disease (NAFLD) is an abnormal liver metabolism often observed with insulin resistance and metabolic… (More)
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Highly Cited
2008
Highly Cited
2008
The NAD(+)-dependent deacetylase SIRT1 controls metabolic processes in response to low nutrient availability. We report the… (More)
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Highly Cited
2008
Highly Cited
2008
Calorie restriction (CR) produces a number of health benefits and ameliorates diseases of aging such as type 2 diabetes. The… (More)
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