SRSF10 gene

During heat shock and other proteotoxic stresses, cells regulate multiple steps in gene expression in order to globally repress… Expand

Metazoan genomes encode hundreds of RNA-binding proteins (RBPs) but RNA-binding preferences for relatively few RBPs have been… Expand

SRp38 is an atypical SR protein splicing regulator. To define the functions of SRp38 in vivo, we generated SRp38 null mice. The… Expand

SRp38 is an atypical SR protein that functions as a general splicing repressor when dephosphorylated. We now show that… Expand

Pathogenic bacteria experience nitrosative stress from NO generated in the host and from nitrosating species such as S… Expand

Although pre-mRNA splicing is known to be regulated by cell signaling, the underlying mechanisms are poorly understood. SRp38 is… Expand

A heat stress causes a rapid inhibition of splicing. Exogenous expression of Hsp27 did not prevent that inhibition but enhanced… Expand

Consistent with its role as a nitric oxide (NO)‐detoxifying globin in Campylobacter jejuni, Cgb (Campylobacter globin) expression… Expand

The cellular response to stresses such as heat shock involves changes in gene expression. It is well known that the splicing of… Expand

SR proteins constitute a family of pre-mRNA splicing factors that play important roles in both constitutive and regulated… Expand