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SREBP signaling pathway

Known as: SREBP-mediated signalling pathway, ER to nucleus sterol response pathway, SREBP target gene transcriptional activation 
A series of molecular signals from the endoplasmic reticulum to the nucleus generated as a consequence of decreased levels of one or more sterols… 
National Institutes of Health

Related topics

Related topics

4 relations
endoplasmic reticulum unfolded protein responsenegative regulation of SREBP signaling pathway by negative regulation of DNA binding

Narrower (2)

sterol regulatory element binding protein cleavagesterol regulatory element binding protein import into nucleus

Papers overview

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Highly Cited
2009
Highly Cited
2009
Dietary soy protein isolate attenuates metabolic syndrome in rats via effects on PPAR, LXR, and SREBP signaling.
To determine the effects of feeding soy or isoflavones on lipid homeostasis in early development, weanling rats were fed AIN-93G… 
Highly Cited
2003
Highly Cited
2003
Total biosynthesis of hydrocortisone from a simple carbon source in yeast
We report on the production of hydrocortisone, the major adrenal glucocorticoid of mammals and an important intermediate of… 
Highly Cited
2002
Highly Cited
2002
Isolation of various forms of sterol β‐d‐glucoside from the seed of Cycas circinalis: neurotoxicity and implications for ALS‐parkinsonism dementia complex
The factors responsible for ALS‐parkinsonism dementia complex (ALS‐PDC), the unique neurological disorder of Guam, remain… 
Highly Cited
2001
Highly Cited
2001
Overlapping functions of the yeast oxysterol-binding protein homologues.
The Saccharomyces cerevisiae genome encodes seven homologues of the mammalian oxysterol-binding protein (OSBP), a protein… 
Highly Cited
2000
Highly Cited
2000
Contribution of Are1p and Are2p to steryl ester synthesis in the yeast Saccharomyces cerevisiae.
In the yeast Saccharomyces cerevisiae, two acyl-CoA:sterol acyltransferases (ASATs) that catalyze the synthesis of steryl esters… 
Review
1999
Review
1999
Neuroactive neurosteroids as endogenous effectors for the sigma1 (sigma1) receptor: pharmacological evidence and therapeutic opportunities.
Neuroactive neurosteroids, including progesterone, allopregnanolone, pregnenolone and dehydroepiandrosterone, represent steroid… 
Highly Cited
1998
Highly Cited
1998
Human lamin B receptor exhibits sterol C14-reductase activity in Saccharomyces cerevisiae.
Highly Cited
1991
Highly Cited
1991
Cloning, disruption and sequence of the gene encoding yeast C-5 sterol desaturase.
Highly Cited
1981
Highly Cited
1981
The effect of various intakes of omega 3 fatty acids on the blood lipid composition in healthy human subjects.
In a study with 52 healthy volunteers, the effect of different amounts of omega 3 fatty acids on the blood lipid composition was… 
Highly Cited
1971
Highly Cited
1971
Lipids of human atheroma. 4. Characterisation of a new group of polar sterol esters from human atherosclerotic plaques.
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