SREBP signaling pathway

Known as: SREBP-mediated signalling pathway, ER to nucleus sterol response pathway, SREBP target gene transcriptional activation 
A series of molecular signals from the endoplasmic reticulum to the nucleus generated as a consequence of decreased levels of one or more sterols… (More)
National Institutes of Health

Papers overview

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2013
2013
The sterol regulatory element-binding proteins (SREBP) are key transcriptional regulators of lipid metabolism and cellular growth… (More)
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Highly Cited
2013
Highly Cited
2013
Most of the human genome is transcribed into protein-noncoding RNAs (ncRNAs), including small ncRNAs and long ncRNAs (lncRNAs… (More)
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Review
2005
Review
2005
Incorporation of plant stanol esters into margarine is among the first examples of a functional food with proven low-density… (More)
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Highly Cited
2003
Highly Cited
2003
Plants have many polarized cell types, but relatively little is known about the mechanisms that establish polarity. The orc… (More)
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Highly Cited
2003
Highly Cited
2003
We report on the production of hydrocortisone, the major adrenal glucocorticoid of mammals and an important intermediate of… (More)
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Highly Cited
2002
Highly Cited
2002
Diacylglycerol esterification provides an excellent target for the pharmacological reduction of triglyceride accumulation in… (More)
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Highly Cited
2002
Highly Cited
2002
In contrast to lipoprotein-mediated sterol uptake, free sterol influx by eukaryotic cells is poorly understood. To identify… (More)
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Highly Cited
1998
Highly Cited
1998
The Smith-Lemli-Opitz syndrome (SLOS; also known as "RSH syndrome" [MIM 270400]) is an autosomal recessive multiple malformation… (More)
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Review
1995
Review
1995
Fungi are among the most primitive organisms that synthesize sterols. The fungal sterol, ergosterol, is similar to animal sterol… (More)
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Highly Cited
1985
Highly Cited
1985
Analyses with a yeast sterol auxotroph indicated that there are at least four different levels of function for sterol which have… (More)
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