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SREBF1 gene

Known as: sterol regulatory element binding transcription factor 1, SREBP1a, SREBF1 
This gene is involved in both transcriptional regulation and lipid homeostasis.
National Institutes of Health

Papers overview

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Highly Cited
2017
Highly Cited
2017
Background The link between DNA methylation, obesity, and adiposity-related diseases in the general population remains uncertain… Expand
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Highly Cited
2014
Highly Cited
2014
Significance This study presents the first results, to our knowledge, of a whole-genome RNAi screen to identify factors that… Expand
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Highly Cited
2011
Highly Cited
2011
Lamin A/C proteins are the major components of a thin proteinaceous filamentous meshwork, the lamina, that underlies the inner… Expand
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Highly Cited
2011
Highly Cited
2011
Activation of AMP-activated protein kinase (AMPK) inhibits hepatic fatty acid synthesis by suppressing sterol regulatory element… Expand
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Highly Cited
2008
Highly Cited
2008
Obesity is characterized by systemic low-grade inflammation in which adipose tissue, especially the omental depot, is thought to… Expand
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Highly Cited
2007
Highly Cited
2007
Hepatic steatosis is a common feature in patients with chronic hepatitis C virus (HCV) infection. HCV core protein plays an… Expand
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Highly Cited
2005
Highly Cited
2005
The sterol regulatory element binding protein (SREBP) family of transcription factors controls cholesterol and lipid metabolism… Expand
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Highly Cited
2004
Highly Cited
2004
Adipogenesis is dependent on the sequential activation of transcription factors including the CCAAT/enhancer-binding proteins (C… Expand
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Highly Cited
2003
Highly Cited
2003
Members of the SREBP family of transcription factors control cholesterol and lipid homeostasis and play important roles during… Expand
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Highly Cited
1995
Highly Cited
1995
Sterol regulatory element binding protein-1 (SREBP1) and SREBP2 are structurally related proteins that control cholesterol… Expand
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