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SPO11 wt Allele

Known as: SPO11, SPO11 Meiotic Protein Covalently Bound to DSB-Like (S. Cerevisiae) wt Allele 
Human SPO11 wild-type allele is located within 20q13.2-q13.3 and is approximately 14 kb in length. This allele, which encodes meiotic recombination… Expand
National Institutes of Health

Papers overview

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2020
2020
Meiotic double-strand breaks (DSBs) are generated by the evolutionarily conserved SPO11 complex in the context of chromatin loops… Expand
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2015
2015
Meiosis as the specialized cell division of sexual reproduction plays a crucial role in the exchange and reorganization of… Expand
2003
2003
  • M. Barchi, M. Jasin
  • Proceedings of the National Academy of Sciences…
  • 2003
  • Corpus ID: 12353626
Human infertility is a major worldwide health problem for individuals and their partners (1). Because genetic defects are thought… Expand
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Highly Cited
1993
Highly Cited
1993
Previous work has shown that cdc13 causes meiotic arrest of Saccharomyces cerevisiae following DNA replication by a RAD9… Expand
1985
1985
We used haploid yeast cells that express both the MATa and MAT alpha mating-type alleles and contain the spo13-1 mutation to… Expand