SPHK1 gene

Known as: Sphingosine Kinase 1 Gene, SPHINGOSINE KINASE 1, SPHK1 
This gene plays a role in lipid phosphorylation and signal transduction.
National Institutes of Health

Papers overview

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2015
2015
Although thousands of long noncoding RNAs (lncRNAs) have been discovered, very little is known about their mode of action. Here… (More)
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Highly Cited
2012
Highly Cited
2012
SPHK1 expression is elevated in gastric cancer and is associated with shorter survival times for patients. However, the molecular… (More)
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2010
Highly Cited
2010
Various studies in cell lines have previously demonstrated that sphingosine kinase 1 (SK1) and extracellular signal-regulated… (More)
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2008
Highly Cited
2008
Under most conditions, resorbed bone is nearly precisely replaced in location and amount by new bone. Thus, it has long been… (More)
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2006
2006
Sphingosine-1-phosophate, generated from the phosphorylation of sphingosine by sphingosine kinase enzymes, is suggested to… (More)
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2004
Highly Cited
2004
Transforming growth factor-beta (TGF-beta) signaling plays a pivotal role in extracellular matrix deposition by stimulating… (More)
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Highly Cited
2004
Highly Cited
2004
Sphingosine-1-phosphate (S1P), a lipid signaling molecule that regulates many cellular functions, is synthesized from sphingosine… (More)
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Highly Cited
2004
Highly Cited
2004
The anaphylatoxin C5a is produced following the activation of the complement system and is associated with a variety of… (More)
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2003
Highly Cited
2003
The immunomodulatory drug FTY720 is phosphorylated in vivo, and the resulting FTY720 phosphate as a ligand for sphingosine-1… (More)
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2003
2003
Sphingosine kinase (SPHK) phosphorylates sphingosine to form a bioactive lipid mediator, sphingosine 1-phosphate (S1P). S1P… (More)
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