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SP 303

Known as: SP-303 
National Institutes of Health

Related topics

Related topics

5 relations

Broader (3)

BiopolymersCatechincrofelemer
Virendanalogs & derivatives

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2005
2005
Increase in intracellular Cl− concentration by cAMP- and Ca2+-dependent stimulation of M1 collecting duct cells
In the lungs of cystic fibrosis (CF) patients, mutations of the cystic fibrosis transmembrane conductance regulator (CFTR) lead… 
Highly Cited
2004
Highly Cited
2004
A novel extract SB-300 from the stem bark latex of Croton lechleri inhibits CFTR-mediated chloride secretion in human colonic epithelial cells.
Highly Cited
2002
Highly Cited
2002
A double blind, randomized, placebo-controlled study of SP-303 (Provir) in the symptomatic treatment of acute diarrhea among travelers to Jamaica and Mexico
OBJECTIVE:The study was designed to evaluate the effectiveness of SP-303 (Provir), a plant-derived product with novel… 
Highly Cited
1999
Highly Cited
1999
A double blind, randomized, placebo-controlled phase II study to assess the safety and efficacy of orally administered SP-303 for the symptomatic treatment of diarrhea in patients with AIDS
Objective:The aim of this study was to investigate the safety and effectiveness of orally administered SP-303 in patients with… 
Highly Cited
1999
Highly Cited
1999
A novel plant-derived inhibitor of cAMP-mediated fluid and chloride secretion.
We have identified an agent (SP-303) that shows efficacy against in vivo cholera toxin-induced fluid secretion and in vitro cAMP… 
1994
1994
Influenza virus-inhibitory effects of intraperitoneally and aerosol-administered SP-303, a plant flavonoid.
The phenolic biopolymer SP-303 was evaluated against experimentally induced influenza A (H1N1) virus infections in mice in a… 
Highly Cited
1994
Highly Cited
1994
SP-303, an antiviral oligomeric proanthocyanidin from the latex of Croton lechleri (Sangre de Drago).
1993
1993
Mode of inhibition of respiratory syncytial virus by a plant flavonoid, SP-303.
A natural-product polyphenolic polymer of molecular weight 2,100 daltons designated SP-303, was found to have antiviral activity… 
1993
1993
The antiviral activity of SP-303, a natural polyphenolic polymer, against respiratory syncytial and parainfluenza type 3 viruses in cotton rats.
1993
1993
SP-303 small-particle aerosol treatment of influenza A virus infection in mice and respiratory syncytial virus infection in cotton rats.
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