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SORCS1 gene

Known as: SORCS RECEPTOR 1, SORCS1, sortilin related VPS10 domain containing receptor 1 
 
National Institutes of Health

Topic mentions per year

Topic mentions per year

2003-2017
01220032017

Papers overview

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2017
2017
[Association between SORCS1 rs1416406 and therapeutic effect of exenatide].
Objective: To study the relationship between SORCS1 gene rs1416406 and efficiency of exenatide. Methods: Between August 2010 and… (More)
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2016
2016
SORCS1 polymorphism and insulin secretion in obese women with polycystic ovary syndrome.
We investigated the influence of SORCS1 polymorphisms on insulin secretion in obese women with PCOS. Metabolic status was… (More)
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2015
2015
SorCS1 variants and amyloid precursor protein (APP) are co-transported in neurons but only SorCS1c modulates anterograde APP transport.
Processing of amyloid precursor protein (APP) into amyloid-β peptide (Aβ) is crucial for the development of Alzheimer's disease… (More)
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2014
2014
SORCS1 is necessary for normal insulin secretory granule biogenesis in metabolically stressed β cells.
We previously positionally cloned Sorcs1 as a diabetes quantitative trait locus. Sorcs1 belongs to the Vacuolar protein sorting… (More)
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2014
2014
Human sorCS1 binds sortilin and hampers its cellular functions.
Sortilin and sorCS1 [sortilin-related Vps10p (vacuolar protein sorting/targeting protein 10) domain-containing receptor 1], both… (More)
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2013
2013
The Genetic Variation of SORCS1 Is Associated with Late-Onset Alzheimer’s Disease in Chinese Han Population
The variations of SORCS1 gene may play potential key roles in late-onset Alzheimer's disease (LOAD). To evaluate the relationship… (More)
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2013
2013
SORCS1 contributes to the development of renal disease in rats and humans.
Many lines of evidence demonstrate that genetic variability contributes to chronic kidney disease susceptibility in humans as… (More)
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2010
2010
Evaluation of four novel genetic variants affecting hemoglobin A1c levels in a population-based type 2 diabetes cohort (the HUNT2 study)
Chronic hyperglycemia confers increased risk for long-term diabetes-associated complications and repeated hemoglobin A1c (HbA1c… (More)
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2009
2009
Genomic convergence to identify candidate genes for Alzheimer disease on chromosome 10.
A broad region of chromosome 10 (chr10) has engendered continued interest in the etiology of late-onset Alzheimer Disease (LOAD… (More)
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2003
2003
Characterization of sorCS1, an alternatively spliced receptor with completely different cytoplasmic domains that mediate different trafficking in cells.
We previously isolated and sequenced murine sorCS1, a type 1 receptor containing a Vps10p-domain and a leucine-rich domain. We… (More)
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