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SORCS1 gene

Known as: SORCS RECEPTOR 1, SORCS1, sortilin related VPS10 domain containing receptor 1 
National Institutes of Health

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2019
2019
Amyloidosis causes downregulation of SorLA, SorCS1 and SorCS3 expression in mice
Abstract Accumulation of β-amyloid peptide (Aβ) is regarded as a primary cause of Alzheimer’s disease (AD). Aβ is derived by… 
2019
2019
Type 2 diabetes-associated single nucleotide polymorphism in Sorcs1 gene results in alternative processing of the Sorcs1 protein in INS1 β-cells
A threonine-to-Isoleucine (Thr52Ile) mutation within the pro-domain of the Sorcs1 gene was positionally cloned as the gene… 
Review
2015
Review
2015
The role of the retromer complex in aging-related neurodegeneration: a molecular and genomic review
The retromer coat complex is a vital component of the intracellular trafficking mechanism sorting cargo from the endosomes to the… 
2014
2014
Human sorCS1 binds sortilin and hampers its cellular functions.
Sortilin and sorCS1 [sortilin-related Vps10p (vacuolar protein sorting/targeting protein 10) domain-containing receptor 1], both… 
2013
2013
SORCS1 contributes to the development of renal disease in rats and humans.
Many lines of evidence demonstrate that genetic variability contributes to chronic kidney disease susceptibility in humans as… 
2013
2013
SORCS 1 contributes to the development of renal disease in rats and humans
Jozef Lazar, Caitlin C. O’Meara, Allison B. Sarkis, Sasha Z. Prisco, Haiyan Xu, Caroline S. Fox, Ming-Huei Chen, Ulrich Broeckel… 
2012
2012
SORCS1 and APOE polymorphisms interact to confer risk for late-onset Alzheimer's disease in a Northern Han Chinese population
2012
2012
Sortilin‐related VPS10 domain containing receptor 1 and Alzheimer's disease‐associated allelic variations preferentially exist in female or type 2 diabetes mellitus patients in southern Han Chinese
Background:  Both in vitro and in vivo, overexpression of the sortilin‐related VPS10 domain containing receptor 1 (SORCS1… 
2011
2011
Impact of Genetic Variation in SORCS1 on Memory Retention
Objective We previously reported that genetic variants in SORCS1 increase the risk of AD, that over-expression of SorCS1 reduces… 
2001
2001
SorCS1, a member of the novel sorting receptor family, is localized in somata and dendrites of neurons throughout the murine brain
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