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Colorectal cancer (CRC) results from histologic and gene alterations can lead to a massive cellular proliferation. Most of the… Expand The most common type of endocrine disease is type 2 diabetes mellitus (T2DM); genetic factors contribute to the development to… Expand Abstract—Reactive oxygen species (ROS) have been implicated in a number of disease processes. Oxidative stress is inhibited by… Expand RATIONALE
Pulmonary hypertension (PH) is a life-threatening disease, characterized by vascular remodeling and vasoconstriction… Expand Inhalation of asbestos fibers leads to interstitial lung disease (asbestosis) characterized by inflammation and fibrosis. The… Expand The antioxidant enzyme extracellular superoxide dismutase (EC-SOD) is highly expressed in the extracellular matrix of lung tissue… Expand Lipoprotein peroxidation in the arterial wall has been implicated in atherogenesis. The superoxide radical is formed in arteries… Expand Clinical and epidemiological studies have provided circumstantial evidence that oxidized low-density lipoprotein (LDL) and… Expand Increasing evidence points out that superoxide dismutase (SOD) isoenzymes play a crucial role in the antioxidative scavenging of… Expand Maintenance of low vascular tone within the placenta is mediated by nitric oxide (NO). The half-life of NO is very short, as… Expand